Literature DB >> 21206411

Periodontal alteration of the microcirculation and hypercholesterolemia: a possible correlation?

Giuseppe Alessandro Scardina1, Teresa Pisano, Antonino Cacioppo, Pietro Messina.   

Abstract

OBJECTIVE: We evaluated the morphological and parametric characteristics of the periodontal microcirculation in patients diagnosed as having hypercholesterolemia and high levels of low-density lipoprotein (LDL).
METHODS: Forty patients were recruited, 20 of whom were affected by hypercholesterolemia and 20 of whom were considered healthy. A videocapillaroscopic examination was carried out on the periodontal mucosa in the proximity of the frenulum (II, V sextant).
RESULTS: The difference between the parameters of the hypercholesterolemia group and the control group was evaluated with the Mann-Whitney U-test for non-parametric ordinal data; the level of significance being P<0.05. The videocapillaroscopy documented extremely significant differences between the two groups, regarding the following parameters: total diameter of the loop (P=0.0017), diameter of the afferent loops (P=0.0004), diameter of the efferent loops (P=0.00008) and periodontal density (P=0.0001).
CONCLUSIONS: The capillaroscopic examination revealed a morphological alteration of the periodontal microcirculation in patients with hypercholesterolemia, which is an expression of peripheral vascular phlogosis.

Entities:  

Mesh:

Substances:

Year:  2011        PMID: 21206411     DOI: 10.1097/SMJ.0b013e318205ddf1

Source DB:  PubMed          Journal:  South Med J        ISSN: 0038-4348            Impact factor:   0.954


  3 in total

1.  Periodontal microcirculation in diabetics: an in vivo non-invasive analysis by means of videocapillaroscopy.

Authors:  Giuseppe Alessandro Scardina; Antonino Cacioppo; Pietro Messina
Journal:  Med Sci Monit       Date:  2012-02

2.  Simvastatin intervention mitigates hypercholesterolemia-induced alveolar bone resorption in rats.

Authors:  Xiaoli Gao; Jianhua Zhou; Yuanyuan Bian; Shengyun Huang; Dongsheng Zhang
Journal:  Exp Ther Med       Date:  2021-04-15       Impact factor: 2.447

3.  The association between hyperlipidemia and periodontal infection.

Authors:  Leila Golpasand Hagh; Faramarz Zakavi; Fatemeh Hajizadeh; Morteza Saleki
Journal:  Iran Red Crescent Med J       Date:  2014-12-25       Impact factor: 0.611

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.