Literature DB >> 21203953

Repurposing an old anti-fungal drug as a Hedgehog inhibitor.

Camilla Giambelli, Dennis Liang Fei, Huaizhi Wang, David J Robbins.   

Abstract

Mesh：

Substances：

Year:  2010        PMID： 21203953      PMCID： PMC4875140          DOI： 10.1007/s13238-010-0063-5

Source DB:  PubMed          Journal:  Protein Cell        ISSN： 1674-800X            Impact factor:   14.870


× No keyword cloud information.
  5 in total

1.  The price of innovation: new estimates of drug development costs.

Authors:  Joseph A DiMasi; Ronald W Hansen; Henry G Grabowski
Journal:  J Health Econ       Date:  2003-03       Impact factor: 3.883

2.  Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth.

Authors:  James Kim; Jean Y Tang; Ruoyu Gong; Jynho Kim; John J Lee; Karl V Clemons; Curtis R Chong; Kris S Chang; Mark Fereshteh; Dale Gardner; Tannishtha Reya; Jun O Liu; Ervin H Epstein; David A Stevens; Philip A Beachy
Journal:  Cancer Cell       Date:  2010-04-13       Impact factor: 31.743

Review 3.  Hedgehog beyond medulloblastoma and basal cell carcinoma.

Authors:  Stephan Teglund; Rune Toftgård
Journal:  Biochim Biophys Acta       Date:  2010-01-18

4.  Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

Authors:  Robert L Yauch; Gerrit J P Dijkgraaf; Bruno Alicke; Thomas Januario; Christina P Ahn; Thomas Holcomb; Kanan Pujara; Jeremy Stinson; Christopher A Callahan; Tracy Tang; J Fernando Bazan; Zhengyan Kan; Somasekar Seshagiri; Christine L Hann; Stephen E Gould; Jennifer A Low; Charles M Rudin; Frederic J de Sauvage
Journal:  Science       Date:  2009-09-02       Impact factor: 47.728

Review 5.  Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond.

Authors:  Hossein A Ghofrani; Ian H Osterloh; Friedrich Grimminger
Journal:  Nat Rev Drug Discov       Date:  2006-08       Impact factor: 84.694
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.