Literature DB >> 21203946

Roles of the hemagglutinin of influenza A virus in viral entry and development of antiviral therapeutics and vaccines.

Shibo Jiang1,2, Runming Li3, Lanying Du4, Shuwen Liu5.   

Abstract

Seasonal influenza epidemics and influenza pandemics caused by influenza A virus (IAV) has resulted in millions of deaths in the world. The development of anti-IAV vaccines and therapeutics is urgently needed for prevention and treatment of IAV infection and for controlling future influenza pandemics. Hemagglutinin (HA) of IAV plays a critical role in viral binding, fusion and entry, and contains the major neutralizing epitopes. Therefore, HA is an attractive target for developing anti-IAV drugs and vaccines. Here we have reviewed the recent progress in study of conformational changes of HA during viral fusion process and development of HA-based antiviral therapeutics and vaccines.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 21203946      PMCID： PMC4728157          DOI： 10.1007/s13238-010-0054-6

Source DB:  PubMed          Journal:  Protein Cell        ISSN： 1674-800X            Impact factor:   14.870


  110 in total

Review 1.  HIV entry inhibitors targeting gp41: from polypeptides to small-molecule compounds.

Authors:  Shuwen Liu; Shuguang Wu; Shibo Jiang
Journal:  Curr Pharm Des       Date:  2007       Impact factor: 3.116

2.  Recombinant parainfluenza virus 5 (PIV5) expressing the influenza A virus hemagglutinin provides immunity in mice to influenza A virus challenge.

Authors:  S Mark Tompkins; Yuan Lin; George P Leser; Kari A Kramer; Debra L Haas; Elizabeth W Howerth; Jie Xu; Mary J Kennett; Russell K Durbin; Joan E Durbin; Ralph Tripp; Robert A Lamb; Biao He
Journal:  Virology       Date:  2007-01-23       Impact factor: 3.616

3.  Differential neutralization efficiency of hemagglutinin epitopes, antibody interference, and the design of influenza vaccines.

Authors:  Wilfred Ndifon; Ned S Wingreen; Simon A Levin
Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-13       Impact factor: 11.205

4.  Stachyflin and acetylstachyflin, novel anti-influenza A virus substances, produced by Stachybotrys sp. RF-7260. II. Synthesis and preliminary structure-activity relationships of stachyflin derivatives.

Authors:  Kazuyuki Minagawa; Shuichi Kouzuki; Toshiyuki Kamigauchi
Journal:  J Antibiot (Tokyo)       Date:  2002-02       Impact factor: 2.649

5.  Inhibition of the fusion-inducing conformational change of influenza hemagglutinin by benzoquinones and hydroquinones.

Authors:  D L Bodian; R B Yamasaki; R L Buswell; J F Stearns; J M White; I D Kuntz
Journal:  Biochemistry       Date:  1993-03-30       Impact factor: 3.162

6.  X-ray crystallographic structure of a papain-leupeptin complex.

Authors:  E Schröder; C Phillips; E Garman; K Harlos; C Crawford
Journal:  FEBS Lett       Date:  1993-01-02       Impact factor: 4.124

7.  Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic.

Authors:  Gavin J D Smith; Dhanasekaran Vijaykrishna; Justin Bahl; Samantha J Lycett; Michael Worobey; Oliver G Pybus; Siu Kit Ma; Chung Lam Cheung; Jayna Raghwani; Samir Bhatt; J S Malik Peiris; Yi Guan; Andrew Rambaut
Journal:  Nature       Date:  2009-06-25       Impact factor: 49.962

8.  Receptor determinants of human and animal influenza virus isolates: differences in receptor specificity of the H3 hemagglutinin based on species of origin.

Authors:  G N Rogers; J C Paulson
Journal:  Virology       Date:  1983-06       Impact factor: 3.616

9.  The origin and virulence of the 1918 "Spanish" influenza virus.

Authors:  Jeffery K Taubenberger
Journal:  Proc Am Philos Soc       Date:  2006-03

Review 10.  Inactivated influenza virus vaccines in children.

Authors:  Frederick L Ruben
Journal:  Clin Infect Dis       Date:  2004-02-17       Impact factor: 9.079
View more
  12 in total

Review 1.  Potential strategies and biosafety protocols used for dual-use research on highly pathogenic influenza viruses.

Authors:  Lanying Du; Ye Li; Jimin Gao; Yusen Zhou; Shibo Jiang
Journal:  Rev Med Virol       Date:  2012-09-14       Impact factor: 6.989

2.  Novel hemagglutinin-based influenza virus inhibitors.

Authors:  Xintian Shen; Xuanxuan Zhang; Shuwen Liu
Journal:  J Thorac Dis       Date:  2013-08       Impact factor: 2.895

3.  Recombinant Lactococcus lactis Expressing Haemagglutinin from a Polish Avian H5N1 Isolate and Its Immunological Effect in Preliminary Animal Trials.

Authors:  Agnieszka K Szczepankowska; Katarzyna Szatraj; Przemysław Sałański; Agnieszka Rózga; Roman K Górecki; Jacek K Bardowski
Journal:  Biomed Res Int       Date:  2017-02-22       Impact factor: 3.411

Review 4.  Zoonotic Potential of Influenza A Viruses: A Comprehensive Overview.

Authors:  Ahmed Mostafa; Elsayed M Abdelwhab; Thomas C Mettenleiter; Stephan Pleschka
Journal:  Viruses       Date:  2018-09-13       Impact factor: 5.048

Review 5.  Influenza A virus entry inhibitors targeting the hemagglutinin.

Authors:  Jie Yang; Minmin Li; Xintian Shen; Shuwen Liu
Journal:  Viruses       Date:  2013-01-22       Impact factor: 5.048

6.  A critical HA1 neutralizing domain of H5N1 influenza in an optimal conformation induces strong cross-protection.

Authors:  Lanying Du; Guangyu Zhao; Shihui Sun; Xiujuan Zhang; Xiaojun Zhou; Yan Guo; Ye Li; Yusen Zhou; Shibo Jiang
Journal:  PLoS One       Date:  2013-01-08       Impact factor: 3.240

7.  HASP server: a database and structural visualization platform for comparative models of influenza A hemagglutinin proteins.

Authors:  Xavier I Ambroggio; Jennifer Dommer; Vivek Gopalan; Eleca J Dunham; Jeffery K Taubenberger; Darrell E Hurt
Journal:  BMC Bioinformatics       Date:  2013-06-18       Impact factor: 3.169

8.  Cathepsin B plays a key role in optimal production of the influenza A virus.

Authors:  Macon D Coleman; Soon-Duck Ha; S M Mansour Haeryfar; Stephen Dominic Barr; Sung Ouk Kim
Journal:  J Virol Antivir Res       Date:  2018-05-11

9.  3DFlu: database of sequence and structural variability of the influenza hemagglutinin at population scale.

Authors:  Giovanni Mazzocco; Michal Lazniewski; Piotr Migdał; Teresa Szczepińska; Jan P Radomski; Dariusz Plewczynski
Journal:  Database (Oxford)       Date:  2016-10-02       Impact factor: 3.451

10.  A Combined NMR-Computational Study of the Interaction between Influenza Virus Hemagglutinin and Sialic Derivatives from Human and Avian Receptors on the Surface of Transfected Cells.

Authors:  Francesca Vasile; Maddalena Panigada; Antonio Siccardi; Donatella Potenza; Guido Tiana
Journal:  Int J Mol Sci       Date:  2018-04-24       Impact factor: 5.923
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.