Literature DB >> 21199407

Routine calcium measurement is not necessary after most thyroid surgeries: a prospective clinical study.

E M Quinn1, P M Neary, O J O'Connor, A Shafiq, J Kelly, H P Redmond.   

Abstract

OBJECTIVES: Calcium levels are often measured to diagnose postoperative hypocalcaemia following thyroidectomy. The aims of this study were to (i) prospectively determine the incidence of symptomatic and biochemical hypocalcaemia following thyroidectomy, (ii) to identify if any associations exist between hypocalcaemia, type of surgery, histological diagnosis, specimen size/weight and the presence of histological parathyroid tissue and (iii) to evaluate the necessity of routine measurement of calcium levels following all thyroidectomies.
DESIGN: Prospective clinical study. SETTINGS: University teaching hospital. PARTICIPANTS: Eighty-six patients presenting consecutively for thyroid surgery. OUTCOME MEASURES: Type of surgery, indications, perioperative calcium levels, symptoms of hypocalcaemia and histology were documented.
RESULTS: Fifty-four patients underwent thyroid lobectomy and isthmusectomy, 19 underwent total and 13 completion thyroidectomy. Significantly, no patient undergoing thyroid lobectomy developed hypocalcaemia versus 26% of total thyroidectomies (P=0.001) and 23% of completion thyroidectomies (P=0.006). All eight patients with hypocalcaemia required treatment. Seven were initially identified clinically. Logistic regression analysis revealed that operation type was the only independent risk factor for developing hypocalcaemia (P=0.021).
CONCLUSIONS: No patient developed hypocalcaemia following thyroid lobectomy and isthmusectomy. Considering the majority (63%) of thyroid surgeries were lobectomies, most patients tested appear low risk for hypocalcaemia. Definitive prediction of hypocalcaemia postoperatively remains a challenge. However, our results suggest that analysing calcium levels routinely following thyroid lobectomy is unwarranted.
© 2010 Blackwell Publishing Ltd.

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Year:  2010        PMID: 21199407     DOI: 10.1111/j.1749-4486.2010.02222.x

Source DB:  PubMed          Journal:  Clin Otolaryngol        ISSN: 1749-4478            Impact factor:   2.597


  4 in total

1.  [Intraoperative parathyroid hormone measurement is the best predictor of postoperative symptomatic hypocalcemia].

Authors:  S Bähler; W Müller; T Linder; A Frotzler; S Fischli; B Aqtashi; F Elmas; A Nader
Journal:  HNO       Date:  2017-12       Impact factor: 1.284

2.  Short-Term Hypocalcemia Prophylaxis With Calcitriol Before Thyroidectomy.

Authors:  Stefanie Sonnenberg; Mandy Scheunchen; Constantin Aurel Smaxwil; Heimo Weih; Christian Vorländer; Peter Langer; Aaltje Ostermann; Katharina Holzer; Andreas Zielke
Journal:  Dtsch Arztebl Int       Date:  2021-11-26       Impact factor: 5.594

3.  Excessive decrease in serum magnesium after total thyroidectomy for Graves' disease is related to development of permanent hypocalcemia.

Authors:  Sara Salehi Hammerstad; Ingrid Norheim; Trond Paulsen; Lise Marit Amlie; Erik Fink Eriksen
Journal:  World J Surg       Date:  2013-02       Impact factor: 3.352

4.  Impact of preoperative Vitamin D3 administration on postoperative hypocalcaemia in patients undergoing total thyroidectomy (HypoCalViD): study protocol for a randomized controlled trial.

Authors:  Stefanie Wolak; Mandy Scheunchen; Katharina Holzer; Mirjam Busch; Esra Trumpf; Andreas Zielke
Journal:  Trials       Date:  2016-02-20       Impact factor: 2.279

  4 in total

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