Literature DB >> 21196421

Integrating genomics into biobehavioral research: a transplantation exemplar.

Carolyn J Driscoll1, Debra Lyon, Nancy L McCain.   

Abstract

Biobehavioral research is becoming more established in nursing. This research paradigm includes a focus on the interactions of biological and behavioral variables and their impact on health outcomes. Nurse researchers have incorporated genomics as a research focus. However, biobehavioral and genomic approaches have often been viewed as separate paradigms. This article provides research exemplars from the liver transplantation population to illustrate how genomics can be integrated into a biobehavioral model of nursing research. Examples of how this integrated approach may be utilized to address gaps of knowledge are provided.

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Year:  2010        PMID: 21196421      PMCID: PMC3966624          DOI: 10.1177/1099800410389603

Source DB:  PubMed          Journal:  Biol Res Nurs        ISSN: 1099-8004            Impact factor:   2.522


  28 in total

1.  Differential expression of chemokines and chemokine receptors shapes the inflammatory response in rejecting human liver transplants.

Authors:  S Goddard; A Williams; C Morland; S Qin; R Gladue; S G Hubscher; D H Adams
Journal:  Transplantation       Date:  2001-12-27       Impact factor: 4.939

Review 2.  Long-term care of the liver allograft recipient.

Authors:  George Mells; James Neuberger
Journal:  Semin Liver Dis       Date:  2009-02-23       Impact factor: 6.115

3.  Long-term medical comorbidities and their management: hypertension/cardiovascular disease.

Authors:  Olaf Guckelberger
Journal:  Liver Transpl       Date:  2009-11       Impact factor: 5.799

4.  The effect of polymorphisms in tumor necrosis factor-alpha, interleukin-10, and transforming growth factor-beta1 genes in acute hepatic allograft rejection.

Authors:  A J Bathgate; V Pravica; C Perrey; G Therapondos; J N Plevris; P C Hayes; I V Hutchinson
Journal:  Transplantation       Date:  2000-04-15       Impact factor: 4.939

5.  Investigation of promoter polymorphisms in the tumor necrosis factor-alpha and interleukin-10 genes in liver transplant patients.

Authors:  Helen Fernandes; Baburao Koneru; Neil Fernandes; Meera Hameed; Marion C Cohen; Elizabeth Raveche; Stanley Cohen
Journal:  Transplantation       Date:  2002-06-27       Impact factor: 4.939

6.  Transplant outcomes and economic costs associated with patient noncompliance to immunosuppression.

Authors:  B W Pinsky; S K Takemoto; K L Lentine; T E Burroughs; M A Schnitzler; P R Salvalaggio
Journal:  Am J Transplant       Date:  2009-11       Impact factor: 8.086

7.  Obesity, hyperlipidemia, and metabolic syndrome.

Authors:  Michael Charlton
Journal:  Liver Transpl       Date:  2009-11       Impact factor: 5.799

8.  Proteomic analysis of HCV cirrhosis and HCV-induced HCC: identifying biomarkers for monitoring HCV-cirrhotic patients awaiting liver transplantation.

Authors:  Valeria R Mas; Daniel G Maluf; Kellie J Archer; Kenneth Yanek; Karen Bornstein; Robert A Fisher
Journal:  Transplantation       Date:  2009-01-15       Impact factor: 4.939

9.  Liver transplantation at the extremes of the body mass index.

Authors:  André A S Dick; Austin L Spitzer; Catherine F Seifert; Alysun Deckert; Robert L Carithers; Jorge D Reyes; James D Perkins
Journal:  Liver Transpl       Date:  2009-08       Impact factor: 5.799

10.  Smoking behavior in liver transplant recipients.

Authors:  Frans van der Heide; Gerard Dijkstra; Robert J Porte; Jan H Kleibeuker; Elizabeth B Haagsma
Journal:  Liver Transpl       Date:  2009-06       Impact factor: 5.799

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