Literature DB >> 21196173

Amino acids and diabetes: implications for endocrine, metabolic and immune function.

Philip Newsholme1, Fernando Abdulkader, Eduardo Rebelato, Talita Romanatto, Carlos Hermano J Pinheiro, Kaio Fernando Vitzel, Erica Portioli Silva, Roberto B Bazotte, Joaquim Procopio, Rui Curi, Renata Gorjao, Tania Cristina Pithon-Curi.   

Abstract

Aberrant alterations in glucose and lipid concentrations and their pathways of metabolism are a hallmark of diabetes. However, much less is known about alterations in concentrations of amino acids and their pathways of metabolism in diabetes. In this review we have attempted to highlight, integrate and discuss common alterations in amino acid metabolism in a wide variety of cells and tissues and relate these changes to alterations in endocrine, physiologic and immune function in diabetes.

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Year:  2011        PMID： 21196173     DOI： 10.2741/3690

Source DB:  PubMed          Journal:  Front Biosci (Landmark Ed)        ISSN： 2768-6698


  15 in total

Review 1.  Dietary essentiality of "nutritionally non-essential amino acids" for animals and humans.

Authors:  Yongqing Hou; Yulong Yin; Guoyao Wu
Journal:  Exp Biol Med (Maywood)       Date:  2015-06-02

Review 2.  Multiligand specificity and wide tissue expression of GPRC6A reveals new endocrine networks.

Authors:  Min Pi; L Darryl Quarles
Journal:  Endocrinology       Date:  2012-02-28       Impact factor: 4.736

3.  Proteome analysis and conditional deletion of the EAAT2 glutamate transporter provide evidence against a role of EAAT2 in pancreatic insulin secretion in mice.

Authors:  Yun Zhou; Leonie F Waanders; Silvia Holmseth; Caiying Guo; Urs V Berger; Yuchuan Li; Anne-Catherine Lehre; Knut P Lehre; Niels C Danbolt
Journal:  J Biol Chem       Date:  2013-11-26       Impact factor: 5.157

4.  Oral supplementations with L-glutamine or L-alanyl-L-glutamine do not change metabolic alterations induced by long-term high-fat diet in the B6.129F2/J mouse model of insulin resistance.

Authors:  Patricia Martins Bock; Mauricio Krause; Helena Trevisan Schroeder; Gabriela Fernandes Hahn; Hilton Kenji Takahashi; Cinthia Maria Schöler; Graziella Nicoletti; Luiz Domingos Zavarize Neto; Maria Inês Lavina Rodrigues; Maciel Alencar Bruxel; Paulo Ivo Homem de Bittencourt
Journal:  Mol Cell Biochem       Date:  2015-11-03       Impact factor: 3.396

5.  Plasma amino acids and oxylipins as potential multi-biomarkers for predicting diabetic macular edema.

Authors:  Sang Youl Rhee; Eun Sung Jung; Dong Ho Suh; Su Jin Jeong; Kiyoung Kim; Suk Chon; Seung-Young Yu; Jeong-Taek Woo; Choong Hwan Lee
Journal:  Sci Rep       Date:  2021-05-06       Impact factor: 4.379

6.  Nutrient excess stimulates β-cell neogenesis in zebrafish.

Authors:  Lisette A Maddison; Wenbiao Chen
Journal:  Diabetes       Date:  2012-06-20       Impact factor: 9.461

7.  Glutamine supplementation stimulates protein-synthetic and inhibits protein-degradative signaling pathways in skeletal muscle of diabetic rats.

Authors:  Adriana C Lambertucci; Rafael H Lambertucci; Sandro M Hirabara; Rui Curi; Anselmo S Moriscot; Tatiana C Alba-Loureiro; Lucas Guimarães-Ferreira; Adriana C Levada-Pires; Diogo A A Vasconcelos; Donald F Sellitti; Tania C Pithon-Curi
Journal:  PLoS One       Date:  2012-12-11       Impact factor: 3.240

8.  A comparison of the effects of oral glutamine dipeptide, glutamine, and alanine on blood amino acid availability in rats submitted to insulin-induced hypoglycemia.

Authors:  Vania C Minguetti-Câmara; Any de C R Marques; Fabiana P M Schiavon; Vanessa R Vilela; Marcos L Bruschi; Roberto Barbosa Bazotte
Journal:  Nutrients       Date:  2014-10-21       Impact factor: 5.717

9.  Reversal of muscle atrophy by Zhimu-Huangbai herb-pair via Akt/mTOR/FoxO3 signal pathway in streptozotocin-induced diabetic mice.

Authors:  Jinbao Zhang; Pengwei Zhuang; Yan Wang; Lili Song; Mixia Zhang; Zhiqiang Lu; Lu Zhang; Jing Wang; Paulos N Alemu; Yanjun Zhang; Hongjun Wei; Hongyan Li
Journal:  PLoS One       Date:  2014-06-26       Impact factor: 3.240

10.  Metabolic profiling of plasma amino acids shows that histidine increases following the consumption of pork.

Authors:  Samir Samman; Ben Crossett; Miles Somers; Kirstine J Bell; Nicole T Lai; David R Sullivan; Peter Petocz
Journal:  Diabetes Metab Syndr Obes       Date:  2014-06-19       Impact factor: 3.168
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