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Literature DB >> 21195613

Chemical affinity matrix-based identification of prohibitin as a binding protein to anti-resorptive sulfonyl amidine compounds.

Sung-Youn Chang¹, Su Jung Bae, Myung Yun Lee, Seung-Hwa Baek, Sukbok Chang, Seong Hwan Kim.

Abstract

In order to identify the binding proteins to anti-resorptive 5-chloro-1-(2,6-dimethylpiperidin-1-yl)-N-tosylpentan-1-imine (1), the chemical affinity matrix for the compound 1 (2b) was designed and synthesized. Using 2b-based chemical proteomics, prohibitin was identified as one of strong binding proteins for 2b. Copyright Â

Entities: Chemical Gene

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Year: 2010 PMID： 21195613 DOI： 10.1016/j.bmcl.2010.11.123

Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823

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Cited

7 in total

Review 1. Studying protein-protein affinity and immobilized ligand-protein affinity interactions using MS-based methods.

Authors: Jeroen Kool; Niels Jonker; Hubertus Irth; Wilfried M A Niessen
Journal: Anal Bioanal Chem Date: 2011-07-14 Impact factor: 4.142

2. Mild Reductive Functionalization of Amides into N-Sulfonylformamidines.

Authors: Paz Trillo; Tove Slagbrand; Fredrik Tinnis; Hans Adolfsson
Journal: ChemistryOpen Date: 2017-07-03 Impact factor: 2.911

3. Assessment of flavaglines as potential chikungunya virus entry inhibitors.

Authors: Phitchayapak Wintachai; Frédéric Thuaud; Christine Basmadjian; Sittiruk Roytrakul; Sukathida Ubol; Laurent Désaubry; Duncan R Smith
Journal: Microbiol Immunol Date: 2015-03 Impact factor: 1.955

4. Design and Synthesis of Novel Podophyllotoxins Hybrids and the Effects of Different Functional Groups on Cytotoxicity.

Authors: Zhongtao Yang; Zitong Zhou; Xiai Luo; Xiaoling Luo; Hui Luo; Lianxiang Luo; Weiguang Yang
Journal: Molecules Date: 2021-12-30 Impact factor: 4.411

Chemical affinity matrix-based identification of prohibitin as a binding protein to anti-resorptive sulfonyl amidine compounds.

Review 1. Studying protein-protein affinity and immobilized ligand-protein affinity interactions using MS-based methods.

2. Mild Reductive Functionalization of Amides into N-Sulfonylformamidines.

3. Assessment of flavaglines as potential chikungunya virus entry inhibitors.

4. Design and Synthesis of Novel Podophyllotoxins Hybrids and the Effects of Different Functional Groups on Cytotoxicity.

Review 5. Small Molecule Inhibitors Targeting Chikungunya Virus.

Review 6. A compendium of small molecule direct-acting and host-targeting inhibitors as therapies against alphaviruses.

Review 7. Prohibitin ligands in cell death and survival: mode of action and therapeutic potential.