Literature DB >> 21194937

Quencher-free molecular beacon: Enhancement of the signal-to-background ratio with graphene oxide.

Jeong Wu Yi1, Jaesung Park, N Jiten Singh, Il Joon Lee, Kwang S Kim, Byeang Hyean Kim.   

Abstract

We report the highly improved version of quencher-free molecular beacon (QF-MB) system by using graphene oxide (GO) as an external quencher. This QF-MB/GO system provided a higher S/B ratio (31.0) relative to that (2.2) of the same system in the absence of GO, while retaining a high selectivity for fully matched over single-base-mismatched targets. Copyright Â
© 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 21194937     DOI: 10.1016/j.bmcl.2010.12.004

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  3 in total

Review 1.  Biosensors based on graphene oxide and its biomedical application.

Authors:  Jieon Lee; Jungho Kim; Seongchan Kim; Dal-Hee Min
Journal:  Adv Drug Deliv Rev       Date:  2016-06-11       Impact factor: 15.470

Review 2.  Graphene Oxide and Biomolecules for the Production of Functional 3D Graphene-Based Materials.

Authors:  Paolo Passaretti
Journal:  Front Mol Biosci       Date:  2022-03-15

Review 3.  An elegant biosensor molecular beacon probe: challenges and recent solutions.

Authors:  Dmitry M Kolpashchikov
Journal:  Scientifica (Cairo)       Date:  2012-12-13
  3 in total

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