Literature DB >> 21194687

Metformin improves semen characteristics of oligo-terato-asthenozoospermic men with metabolic syndrome.

Giuseppe Morgante1, Claudia Tosti, Raoul Orvieto, Maria C Musacchio, Paola Piomboni, Vincenzo De Leo.   

Abstract

To examine the appropriate treatment of oligo-terato-asthenozoospermic patients with metabolic syndrome, 45 patients were treated with metformin for 6 months. The use of metformin was associated with a statistically significant reduction in insulin resistance and sex hormone-binding globulin levels, a statistically significant increase in serum androgen levels, and a consequent improvement in semen characteristics.
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID： 21194687     DOI： 10.1016/j.fertnstert.2010.12.009

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  20 in total

1.  Protective effects of metformin on reproductive function in obese male rats induced by high-fat diet.

Authors:  Wen-jie Yan; Yang Mu; Nan Yu; Tai-lang Yi; Yi Zhang; Xiang-li Pang; Dan Cheng; Jing Yang
Journal:  J Assist Reprod Genet       Date:  2015-06-17       Impact factor: 3.412

2.  Paternal physical and sedentary activities in relation to semen quality and reproductive outcomes among couples from a fertility center.

Authors:  A J Gaskins; M C Afeiche; R Hauser; P L Williams; M W Gillman; C Tanrikut; J C Petrozza; J E Chavarro
Journal:  Hum Reprod       Date:  2014-08-27       Impact factor: 6.918

Review 3.  The role of leptin and low testosterone in obesity.

Authors:  Kajal Khodamoradi; Zahra Khosravizadeh; Deepa Seetharam; Suresh Mallepalli; Natoli Farber; Himanshu Arora
Journal:  Int J Impot Res       Date:  2022-01-31       Impact factor: 2.408

4.  Serum Metabolomic Profiling Identifies Characterization of Non-Obstructive Azoospermic Men.

Authors:  Zhe Zhang; Yingwei Zhang; Changjie Liu; Mingming Zhao; Yuzhuo Yang; Han Wu; Hongliang Zhang; Haocheng Lin; Lemin Zheng; Hui Jiang
Journal:  Int J Mol Sci       Date:  2017-01-25       Impact factor: 5.923

Review 5.  Metformin in Reproductive Biology.

Authors:  Melanie Faure; Michael J Bertoldo; Rita Khoueiry; Alice Bongrani; François Brion; Cecilia Giulivi; Joelle Dupont; Pascal Froment
Journal:  Front Endocrinol (Lausanne)       Date:  2018-11-22       Impact factor: 5.555

Review 6.  Metabolic Disorders and Male Hypogonadotropic Hypogonadism.

Authors:  Rosario Pivonello; Davide Menafra; Enrico Riccio; Francesco Garifalos; Marco Mazzella; Cristina de Angelis; Annamaria Colao
Journal:  Front Endocrinol (Lausanne)       Date:  2019-07-25       Impact factor: 5.555

7.  Association between high-fat diet feeding and male fertility in high reproductive performance mice.

Authors:  M D Gómez-Elías; T S Rainero Cáceres; M M Giaccagli; V A Guazzone; G N Dalton; A De Siervi; P S Cuasnicú; D J Cohen; V G Da Ros
Journal:  Sci Rep       Date:  2019-12-06       Impact factor: 4.379

8.  Metformin Ameliorates Testicular Function and Spermatogenesis in Male Mice with High-Fat and High-Cholesterol Diet-Induced Obesity.

Authors:  Chin-Yu Liu; Ting-Chia Chang; Shyh-Hsiang Lin; Sheng-Tang Wu; Tai-Lung Cha; Chih-Wei Tsao
Journal:  Nutrients       Date:  2020-06-29       Impact factor: 5.717

Review 9.  Androgen deficiency and metabolic syndrome in men.

Authors:  Ashley G Winter; Fujun Zhao; Richard K Lee
Journal:  Transl Androl Urol       Date:  2014-03

10.  Metabolic syndrome in White-European men presenting for secondary couple's infertility: an investigation of the clinical and reproductive burden.

Authors:  Eugenio Ventimiglia; Paolo Capogrosso; Alessandro Serino; Luca Boeri; Michele Colicchia; Giovanni La Croce; Roberta Scano; Enrico Papaleo; Rocco Damiano; Francesco Montorsi; Andrea Salonia
Journal:  Asian J Androl       Date:  2017 May-Jun       Impact factor: 3.285
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