Literature DB >> 21193862

Anticancer drugs: blocking phospholipid-protein interactions.

Charlotte Harrison.   

Abstract

Entities:  

Year:  2011        PMID： 21193862     DOI： 10.1038/nrd3343

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  2 in total

1.  Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains.

Authors:  Benchun Miao; Igor Skidan; Jinsheng Yang; Alexey Lugovskoy; Mikhail Reibarkh; Kai Long; Tres Brazell; Kulbhushan A Durugkar; Jenny Maki; C V Ramana; Brian Schaffhausen; Gerhard Wagner; Vladimir Torchilin; Junying Yuan; Alexei Degterev
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-01       Impact factor: 11.205

Review 2.  Targeting the phosphoinositide 3-kinase pathway in cancer.

Authors:  Pixu Liu; Hailing Cheng; Thomas M Roberts; Jean J Zhao
Journal:  Nat Rev Drug Discov       Date:  2009-08       Impact factor: 84.694
  2 in total
  1 in total

1.  SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1.

Authors:  Yuichiro Yoshioka; Takehiro Suzuki; Yo Matsuo; Makoto Nakakido; Giichiro Tsurita; Cristiano Simone; Toshiaki Watanabe; Naoshi Dohmae; Yusuke Nakamura; Ryuji Hamamoto
Journal:  Oncotarget       Date:  2016-11-15
  1 in total

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