Literature DB >> 21192193

Xylometazoline abuse induced ischemic stroke in a young adult.

Daniela Leupold1, Katja E Wartenberg.   

Abstract

INTRODUCTION: substance abuse is an important cause of ischemic stroke in the young. This includes over-the-counter dietary supplements and cough and cold remedies, which were reported to be an independent risk factor for hemorrhagic stroke. CASE REPORT: this article describes a young male patient with acute ischemic infarctions in the posterior inferior cerebellar and posterior cerebral artery territories bilaterally, the right cerebral peduncle, the left pontine tegmentum, and lateral pons following abuse of xylometazoline-containing nasal decongestant for 10 years.
CONCLUSION: this is the first report in the literature of posterior circulation strokes because of chronic xylometazoline abuse. We hope to contribute to increase knowledge and awareness of the public about these serious complications of cough-and-cold remedies as well as dietary supplements containing sympathomimetics.

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Year:  2011        PMID: 21192193     DOI: 10.1097/NRL.0b013e3181d2ab04

Source DB:  PubMed          Journal:  Neurologist        ISSN: 1074-7931            Impact factor:   1.398


  4 in total

Review 1.  Comprehensive review of cardiovascular toxicity of drugs and related agents.

Authors:  Přemysl Mladěnka; Lenka Applová; Jiří Patočka; Vera Marisa Costa; Fernando Remiao; Jana Pourová; Aleš Mladěnka; Jana Karlíčková; Luděk Jahodář; Marie Vopršalová; Kurt J Varner; Martin Štěrba
Journal:  Med Res Rev       Date:  2018-01-05       Impact factor: 12.944

2.  Effect of withdrawal of fusafungine from the market on prescribing of antibiotics and other alternative treatments in Germany: a pharmacovigilance impact study.

Authors:  Karin Hedenmalm; Xavier Kurz; Daniel Morales
Journal:  Eur J Clin Pharmacol       Date:  2019-03-05       Impact factor: 2.953

3.  Oxymetazoline Metered Dose Spray: Factors Affecting Delivery Volume.

Authors:  Mumin Hakim; Hina Walia; Mahmood Rafiq; Timothy Grannell; Richard S Cartabuke; Joseph D Tobias
Journal:  J Pediatr Pharmacol Ther       Date:  2016 May-Jun

4.  Ischemic Stroke Associated with Chronic Xylometazoline Nasal Spray Misuse: A Rare Avoidable Adverse Event.

Authors:  Jalpan Patel; Ishani Patel; Devangi Desai; Soaham Desai
Journal:  Ann Indian Acad Neurol       Date:  2020-07-08       Impact factor: 1.383

  4 in total

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