Literature DB >> 21191544

Role of genomics in cardiovascular medicine.

Giuseppe Novelli1, Irene M Predazzi, Ruggiero Mango, Francesco Romeo, Jawahar L Mehta.   

Abstract

As all branches of science grow and new experimental techniques become readily accessible, our knowledge of medicine is likely to increase exponentially in the coming years. Recently developed technologies have revolutionized our analytical capacities, leading to vast knowledge of many genes or genomic regions involved in the pathogenesis of congenital heart diseases, which are often associated with other genetic syndromes, coronary artery disease and non-ischemic cardiomyopathies and channelopathies. The knowledge-base of the genesis of cardiovascular diseases is likely going to be further revolutionized in this new era of genomic medicine. Here, we review the advances that have been made over the last several years in this field and discuss different genetic mechanisms that have been shown to underlie a variety of cardiovascular diseases.

Entities:  

Keywords:  Atherosclerosis; Complex diseases; Genomics; Mutations; Polymorphisms

Year:  2010        PMID: 21191544      PMCID: PMC3011138          DOI: 10.4330/wjc.v2.i12.428

Source DB:  PubMed          Journal:  World J Cardiol


  68 in total

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Journal:  Nat Genet       Date:  2000-03       Impact factor: 38.330

2.  Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1.

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Journal:  Nat Genet       Date:  1997-07       Impact factor: 38.330

Review 3.  Cardiac channelopathies.

Authors:  Eduardo Marbán
Journal:  Nature       Date:  2002-01-10       Impact factor: 49.962

Review 4.  MicroRNAs and ischemic heart disease: towards a better comprehension of pathogenesis, new diagnostic tools and new therapeutic targets.

Authors:  Pasquale Silvestri; Cristian Di Russo; Stefano Rigattieri; Silvio Fedele; Daniel Todaro; Giuseppe Ferraiuolo; Giuliano Altamura; Paolo Loschiavo
Journal:  Recent Pat Cardiovasc Drug Discov       Date:  2009-06

5.  Sudden cardiac death in the United States, 1989 to 1998.

Authors:  Z J Zheng; J B Croft; W H Giles; G A Mensah
Journal:  Circulation       Date:  2001-10-30       Impact factor: 29.690

6.  CFC1 mutations in patients with transposition of the great arteries and double-outlet right ventricle.

Authors:  Elizabeth Goldmuntz; Richard Bamford; Jayaprakash D Karkera; June dela Cruz; Erich Roessler; Maximilian Muenke
Journal:  Am J Hum Genet       Date:  2002-01-17       Impact factor: 11.025

7.  X-linked transposition of the great arteries and incomplete penetrance among males with a nonsense mutation in ZIC3.

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Journal:  Eur J Hum Genet       Date:  2000-09       Impact factor: 4.246

8.  Disclosure of APOE genotype for risk of Alzheimer's disease.

Authors:  Robert C Green; J Scott Roberts; L Adrienne Cupples; Norman R Relkin; Peter J Whitehouse; Tamsen Brown; Susan LaRusse Eckert; Melissa Butson; A Dessa Sadovnick; Kimberly A Quaid; Clara Chen; Robert Cook-Deegan; Lindsay A Farrer
Journal:  N Engl J Med       Date:  2009-07-16       Impact factor: 91.245

9.  Mutations in two nonhomologous genes in a head-to-head configuration cause Ellis-van Creveld syndrome.

Authors:  Victor L Ruiz-Perez; Stuart W J Tompson; Helen J Blair; Cecilia Espinoza-Valdez; Pablo Lapunzina; Elias O Silva; Ben Hamel; John L Gibbs; Ian D Young; Michael J Wright; Judith A Goodship
Journal:  Am J Hum Genet       Date:  2003-02-04       Impact factor: 11.025

10.  Genome-wide association study of intracranial aneurysm identifies three new risk loci.

Authors:  Katsuhito Yasuno; Kaya Bilguvar; Philippe Bijlenga; Siew-Kee Low; Boris Krischek; Georg Auburger; Matthias Simon; Dietmar Krex; Zulfikar Arlier; Nikhil Nayak; Ynte M Ruigrok; Mika Niemelä; Atsushi Tajima; Mikael von und zu Fraunberg; Tamás Dóczi; Florentina Wirjatijasa; Akira Hata; Jordi Blasco; Agi Oszvald; Hidetoshi Kasuya; Gulam Zilani; Beate Schoch; Pankaj Singh; Carsten Stüer; Roelof Risselada; Jürgen Beck; Teresa Sola; Filomena Ricciardi; Arpo Aromaa; Thomas Illig; Stefan Schreiber; Cornelia M van Duijn; Leonard H van den Berg; Claire Perret; Carole Proust; Constantin Roder; Ali K Ozturk; Emília Gaál; Daniela Berg; Christof Geisen; Christoph M Friedrich; Paul Summers; Alejandro F Frangi; Matthew W State; H Erich Wichmann; Monique M B Breteler; Cisca Wijmenga; Shrikant Mane; Leena Peltonen; Vivas Elio; Miriam C J M Sturkenboom; Patricia Lawford; James Byrne; Juan Macho; Erol I Sandalcioglu; Bernhard Meyer; Andreas Raabe; Helmuth Steinmetz; Daniel Rüfenacht; Juha E Jääskeläinen; Juha Hernesniemi; Gabriel J E Rinkel; Hitoshi Zembutsu; Ituro Inoue; Aarno Palotie; François Cambien; Yusuke Nakamura; Richard P Lifton; Murat Günel
Journal:  Nat Genet       Date:  2010-04-04       Impact factor: 38.330

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  6 in total

Review 1.  Suppression Subtractive Hybridization Versus Next-Generation Sequencing in Plant Genetic Engineering: Challenges and Perspectives.

Authors:  Mahbod Sahebi; Mohamed M Hanafi; Parisa Azizi; Abdul Hakim; Sadegh Ashkani; Rambod Abiri
Journal:  Mol Biotechnol       Date:  2015-10       Impact factor: 2.695

2.  WDR1 and CLNK gene polymorphisms correlate with serum glucose and high-density lipoprotein levels in Tibetan gout patients.

Authors:  Bing Lan; Peng Chen; Mutu Jiri; Na He; Tian Feng; Kai Liu; Tianbo Jin; Longli Kang
Journal:  Rheumatol Int       Date:  2015-10-05       Impact factor: 2.631

Review 3.  The impact of next-generation sequencing on genomics.

Authors:  Jun Zhang; Rod Chiodini; Ahmed Badr; Genfa Zhang
Journal:  J Genet Genomics       Date:  2011-03-15       Impact factor: 4.275

Review 4.  Human genetics of diabetic vascular complications.

Authors:  Zi-Hui Tang; Zhou Fang; Linuo Zhou
Journal:  J Genet       Date:  2013-12       Impact factor: 1.166

5.  RNA-seq driven expression and enrichment analysis to investigate CVD genes with associated phenotypes among high-risk heart failure patients.

Authors:  Zeeshan Ahmed; Saman Zeeshan; Bruce T Liang
Journal:  Hum Genomics       Date:  2021-11-13       Impact factor: 4.639

Review 6.  Artificial Intelligence and Cardiovascular Genetics.

Authors:  Chayakrit Krittanawong; Kipp W Johnson; Edward Choi; Scott Kaplin; Eric Venner; Mullai Murugan; Zhen Wang; Benjamin S Glicksberg; Christopher I Amos; Michael C Schatz; W H Wilson Tang
Journal:  Life (Basel)       Date:  2022-02-14
  6 in total

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