Literature DB >> 21191525

Evidence-based addiction medicine: the use of lofexidine for opioid detoxification.

Babatunde Adetunji1, Maju Mathews, Adedapo Williams, Olusanya Rufai.   

Abstract

Is there any evidence that lofexidine is as effective as and better tolerated than clonidine for opiate detoxification? Could lofexidine be safely combined with other agents in the management of withdrawal? The purpose of this review is to seek answers to these postulates by using evidence-based testimony.

Entities:  

Year:  2004        PMID： 21191525      PMCID： PMC3010961     

Source DB:  PubMed          Journal:  Psychiatry (Edgmont)        ISSN： 1550-5952


  15 in total

1.  Inpatient opiate detoxification in Geneva: follow-up at 1 and 6 months.

Authors:  B Broers; F Giner; P Dumont; A Mino
Journal:  Drug Alcohol Depend       Date:  2000-02-01       Impact factor: 4.492

2.  Major disruptions of sleep during treatment of the opiate withdrawal syndrome: differences between methadone and lofexidine detoxification treatments.

Authors:  Tracy Beswick; David Best; Sian Rees; Jenny Bearn; Michael Gossop; John Strang
Journal:  Addict Biol       Date:  2003-03       Impact factor: 4.280

3.  A naturalistic study of home detoxification from opiates using lofexidine.

Authors:  A S Brown; P M Fleming
Journal:  J Psychopharmacol       Date:  1998       Impact factor: 4.153

4.  Double-blind study of lofexidine and clonidine in the detoxification of opiate addicts in hospital.

Authors:  A Kahn; J P Mumford; G A Rogers; H Beckford
Journal:  Drug Alcohol Depend       Date:  1997-01-10       Impact factor: 4.492

5.  Two methods of community detoxification from opiates: an open-label comparison of lofexidine and buprenorphine.

Authors:  R White; R Alcorn; C Feinmann
Journal:  Drug Alcohol Depend       Date:  2001-12-01       Impact factor: 4.492

6.  The use of lofexidine by drug dependency units in the United Kingdom.

Authors:  J S Akhurst
Journal:  Eur Addict Res       Date:  1999-03       Impact factor: 3.015

7.  Randomised double-blind comparison of lofexidine and methadone in the in-patient treatment of opiate withdrawal.

Authors:  J Bearn; M Gossop; J Strang
Journal:  Drug Alcohol Depend       Date:  1996-12-02       Impact factor: 4.492

8.  The effectiveness of combined naloxone/lofexidine in opiate detoxification: results from a double-blind randomized and placebo-controlled trial.

Authors:  Tracy Beswick; David Best; Jenny Bearn; Michael Gossop; Sian Rees; John Strang
Journal:  Am J Addict       Date:  2003 Jul-Sep

9.  Double-blind randomised controlled trial of lofexidine versus clonidine in the treatment of heroin withdrawal.

Authors:  S K Lin; J Strang; L W Su; C J Tsai; W H Hu
Journal:  Drug Alcohol Depend       Date:  1997-11-25       Impact factor: 4.492

10.  Evaluation of the effects of lofexidine and clonidine on naloxone-precipitated withdrawal in opioid-dependent humans.

Authors:  Sharon L Walsh; Eric C Strain; George E Bigelow
Journal:  Addiction       Date:  2003-04       Impact factor: 6.526
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