Literature DB >> 21191512

Gastroesophageal reflux disease: Important considerations for the older patients.

Maxwell M Chait1.   

Abstract

Gastroesophageal reflux disease (GERD) is the most common upper gastrointestinal disorder seen in the elderly. The worldwide incidence of GERD is increasing as the incidence of Helicobacter pylori is decreasing. Although elderly patients with GERD have fewer symptoms, their disease is more often severe. They have more esophageal and extraesophageal complications that may be potentially life threatening. Esophageal complications include erosive esophagitis, esophageal stricture, Barrett's esophagus and adenocarcinoma of the esophagus. Extraesophageal complications include atypical chest pain that can simulate angina pectoris; ear, nose, and throat manifestations such as globus sensation, laryngitis, and dental problems; pulmonary problems such as chronic cough, asthma, and pulmonary aspiration. A more aggressive approach may be warranted in the elderly patient, because of the higher incidence of severe complications. Although the evaluation and management of GERD are generally the same in elderly patients as for all adults, there are specific issues of causation, evaluation and treatment that must be considered when dealing with the elderly.

Entities:  

Keywords:  Elderly; Gastroesophageal reflux disease; Older patient

Year:  2010        PMID: 21191512      PMCID: PMC3010469          DOI: 10.4253/wjge.v2.i12.388

Source DB:  PubMed          Journal:  World J Gastrointest Endosc


  51 in total

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Authors:  Yasuhiro Fujiwara; Kazuhide Higuchi; Yoko Watanabe; Masatsugu Shiba; Toshio Watanabe; Kazunari Tominaga; Nobuhide Oshitani; Takayuki Matsumoto; Hideki Nishikawa; Tetsuo Arakawa
Journal:  J Gastroenterol Hepatol       Date:  2005-01       Impact factor: 4.029

2.  Body-mass index and symptoms of gastroesophageal reflux in women.

Authors:  Brian C Jacobson; Samuel C Somers; Charles S Fuchs; Ciarán P Kelly; Carlos A Camargo
Journal:  N Engl J Med       Date:  2006-06-01       Impact factor: 91.245

3.  Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma.

Authors:  J Lagergren; R Bergström; A Lindgren; O Nyrén
Journal:  N Engl J Med       Date:  1999-03-18       Impact factor: 91.245

4.  The impact of nocturnal symptoms associated with gastroesophageal reflux disease on health-related quality of life.

Authors:  C Farup; L Kleinman; S Sloan; D Ganoczy; E Chee; C Lee; D Revicki
Journal:  Arch Intern Med       Date:  2001-01-08

Review 5.  Reflux events and sleep: are we vulnerable?

Authors:  William C Orr
Journal:  Curr Gastroenterol Rep       Date:  2006-06

6.  The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus.

Authors:  Nimish Vakil; Sander V van Zanten; Peter Kahrilas; John Dent; Roger Jones
Journal:  Am J Gastroenterol       Date:  2006-08       Impact factor: 10.864

Review 7.  Definition and diagnosis of gastroesophageal reflux disease.

Authors:  Wai-Man Wong; Benjamin Chun-Yu Wong
Journal:  J Gastroenterol Hepatol       Date:  2004-09       Impact factor: 4.029

Review 8.  Proton pump inhibitors and bone fractures?

Authors:  Loren Laine
Journal:  Am J Gastroenterol       Date:  2009-03       Impact factor: 10.864

9.  Relationship of gastric Helicobacter pylori infection to Barrett's esophagus and gastro-esophageal reflux disease in Chinese.

Authors:  Jun Zhang; Xiao-Li Chen; Kang-Min Wang; Xiao-Dan Guo; Ai-Li Zuo; Jun Gong
Journal:  World J Gastroenterol       Date:  2004-03-01       Impact factor: 5.742

10.  Heartburn severity underestimates erosive esophagitis severity in elderly patients with gastroesophageal reflux disease.

Authors:  David A Johnson; M Brian Fennerty
Journal:  Gastroenterology       Date:  2004-03       Impact factor: 22.682

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  22 in total

1.  The combined effect of age and body mass index on outcomes in foregut surgery: a regression model analysis of the National Surgical Quality Improvement Program data.

Authors:  Prashanth Palvannan; Irving Miranda; Aziz M Merchant
Journal:  Surg Endosc       Date:  2015-09-16       Impact factor: 4.584

2.  Older Age Reduces Upper Esophageal Sphincter and Esophageal Body Responses to Simulated Slow and Ultraslow Reflux Events and Post-Reflux Residue.

Authors:  Ling Mei; Arshish Dua; Mark Kern; Siyuan Gao; Francis Edeani; Kulwinder Dua; Amy Wilson; Shaina Lynch; Patrick Sanvanson; Reza Shaker
Journal:  Gastroenterology       Date:  2018-05-24       Impact factor: 22.682

3.  Sedation-associated hiccups in adults undergoing gastrointestinal endoscopy and colonoscopy.

Authors:  Chien Cheng Liu; Cheng Yuan Lu; Chih Fang Changchien; Ping Hsin Liu; Daw Shyong Perng
Journal:  World J Gastroenterol       Date:  2012-07-21       Impact factor: 5.742

4.  Impact of Laparoscopic Sleeve Gastrectomy on Gastroesophageal Reflux Disease and Risk Factors Associated with Its Occurrence Based Upon Quality of Life.

Authors:  Abdullah Dalboh; Dafer M Al-Shehri; Walid M Abd El Maksoud; Khaled S Abbas; Abdulrahman J Alqahtani; Adnan Q Al-Malki; Khalid A Al-Shahrani
Journal:  Obes Surg       Date:  2021-03-29       Impact factor: 4.129

5.  Proanthocyanidins mitigate bile acid-induced changes in GSTT2 levels in a panel of racially diverse patient-derived primary esophageal cell cultures.

Authors:  Katherine M Weh; Danielle K Turgeon; Joel H Rubenstein; Jennifer L Clarke; Amy B Howell; Andrew C Chang; Laura A Kresty
Journal:  Mol Carcinog       Date:  2021-11-10       Impact factor: 4.784

Review 6.  Management of Gastroesophageal Reflux Disease in the Elderly Patient.

Authors:  Michael Kurin; Ronnie Fass
Journal:  Drugs Aging       Date:  2019-12       Impact factor: 3.923

Review 7.  Gastroesophageal reflux and congenital gastrointestinal malformations.

Authors:  Lucia Marseglia; Sara Manti; Gabriella D'Angelo; Eloisa Gitto; Carmelo Salpietro; Antonio Centorrino; Gianfranco Scalfari; Giuseppe Santoro; Pietro Impellizzeri; Carmelo Romeo
Journal:  World J Gastroenterol       Date:  2015-07-28       Impact factor: 5.742

8.  Lung function parameters in patients with gastroesophageal reflux without respiratory symptoms: a case-control study.

Authors:  Masoud Nazemiyeh; Masoud Nouri-Vaskeh; Mohammad Hossein Somi; Ehsan Saeedi; Akbar Sharifi
Journal:  Gastroenterol Hepatol Bed Bench       Date:  2019

9.  Effect of a Combination of Omeprazole Plus Sustained Release Baclofen Versus Omeprazole Alone on Symptoms of Patients with Gastroesophageal Reflux Disease (GERD).

Authors:  Mohammad Abbasinazari; Yunes Panahi; Seyed Alireza Mortazavi; Fanak Fahimi; Ghasem Valizadegan; Reza Mohtashami; Mohammad Amin Pourhoseingholi; Kambiz Shirvani Bakhtiari
Journal:  Iran J Pharm Res       Date:  2014       Impact factor: 1.696

10.  GERD in elderly patients: surgical treatment with Nissen-Rossetti laparoscopic technique, outcome.

Authors:  Giovanni Aprea; Antonio Ferronetti; Alfonso Canfora; Fabrizio Cardin; Antonio Giugliano; Francesco Guida; Antonio Braun; Melania Battaglini Ciciriello; Federica Tovecci; Giovanni Mastrobuoni; Bruno Amato
Journal:  BMC Surg       Date:  2012-11-15       Impact factor: 2.102

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