Understanding schizoaffective disorder: from psychobiology to psychosocial functioning.

Psychobiologic evidence and psychosocial functioning in patients with schizoaffective disorder suggest that the disease may be a distinct disorder, a variant of schizophrenia or affective disorders, the comorbidity of schizophrenia and a mood disorder, or an intermediate disorder on a spectrum that ranges from schizophrenia to mood disorders. These data, although inconclusive, contribute to clinicians' understanding of the etiology of the disorder. Further research may lead to an increased understanding of the disorder, improved treatment, and, ultimately, better outcomes. © Copyright 2010 Physicians Postgraduate Press, Inc.