| Literature DB >> 21187114 |
Kathryn H Rosenbluth1, Matthias Luz, Erich Mohr, Stephan Mittermeyer, John Bringas, Krystof S Bankiewicz.
Abstract
Failures of recent convection-enhanced delivery (CED) trials have underscored the need for improved CED cannulae. This study presents a novel in-dwelling cannula targeted for use in upcoming neuro-oncological or neurodegeneration trials. The cannula is reflux-resistant and easily integrated into clinical workflows. The cannula was evaluated in non-human primate CED studies performed with magnetic resonance imaging (MRI) to validate the effectiveness and safety of the infusion.Entities:
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Year: 2010 PMID: 21187114 DOI: 10.1016/j.jneumeth.2010.12.022
Source DB: PubMed Journal: J Neurosci Methods ISSN: 0165-0270 Impact factor: 2.390