Literature DB >> 21187114

Design of an in-dwelling cannula for convection-enhanced delivery.

Kathryn H Rosenbluth1, Matthias Luz, Erich Mohr, Stephan Mittermeyer, John Bringas, Krystof S Bankiewicz.   

Abstract

Failures of recent convection-enhanced delivery (CED) trials have underscored the need for improved CED cannulae. This study presents a novel in-dwelling cannula targeted for use in upcoming neuro-oncological or neurodegeneration trials. The cannula is reflux-resistant and easily integrated into clinical workflows. The cannula was evaluated in non-human primate CED studies performed with magnetic resonance imaging (MRI) to validate the effectiveness and safety of the infusion.
Copyright © 2011. Published by Elsevier B.V.

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Year:  2010        PMID: 21187114     DOI: 10.1016/j.jneumeth.2010.12.022

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN: 0165-0270            Impact factor:   2.390


  11 in total

1.  Analysis of a simulation algorithm for direct brain drug delivery.

Authors:  Kathryn Hammond Rosenbluth; Jan Felix Eschermann; Gabriele Mittermeyer; Rowena Thomson; Stephan Mittermeyer; Krystof S Bankiewicz
Journal:  Neuroimage       Date:  2011-09-14       Impact factor: 6.556

2.  In vivo evaluation of needle force and friction stress during insertion at varying insertion speed into the brain.

Authors:  Fernando Casanova; Paul R Carney; Malisa Sarntinoranont
Journal:  J Neurosci Methods       Date:  2014-08-20       Impact factor: 2.390

3.  Intraneural convection enhanced delivery of AAVrh20 for targeting primary sensory neurons.

Authors:  Josef Pleticha; Christian Jeng-Singh; Rahaf Rezek; Manal Zaibak; Andreas S Beutler
Journal:  Mol Cell Neurosci       Date:  2014-04-24       Impact factor: 4.314

4.  Convection-enhanced delivery of M13 bacteriophage to the brain.

Authors:  Alexander Ksendzovsky; Stuart Walbridge; Richard C Saunders; Ashok R Asthagiri; John D Heiss; Russell R Lonser
Journal:  J Neurosurg       Date:  2012-05-18       Impact factor: 5.115

5.  Minimally invasive convection-enhanced delivery of biologics into dorsal root ganglia: validation in the pig model and prospective modeling in humans. Technical note.

Authors:  Josef Pleticha; Timothy P Maus; Jodie A Christner; Michael P Marsh; Kendall H Lee; W Michael Hooten; Andreas S Beutler
Journal:  J Neurosurg       Date:  2014-07-04       Impact factor: 5.115

Review 6.  Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier.

Authors:  David S Hersh; Aniket S Wadajkar; Nathan Roberts; Jimena G Perez; Nina P Connolly; Victor Frenkel; Jeffrey A Winkles; Graeme F Woodworth; Anthony J Kim
Journal:  Curr Pharm Des       Date:  2016       Impact factor: 3.116

7.  Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease.

Authors:  Piotr Hadaczek; Lisa Stanek; Agnieszka Ciesielska; Vivek Sudhakar; Lluis Samaranch; Philip Pivirotto; John Bringas; Catherine O'Riordan; Bryan Mastis; Waldy San Sebastian; John Forsayeth; Seng H Cheng; Krystof S Bankiewicz; Lamya S Shihabuddin
Journal:  Mol Ther Methods Clin Dev       Date:  2016-06-29       Impact factor: 6.698

8.  Magnetic Resonance Imaging-Guided Delivery of Neural Stem Cells into the Basal Ganglia of Nonhuman Primates Reveals a Pulsatile Mode of Cell Dispersion.

Authors:  Kristen E Malloy; Jinqi Li; Gourav R Choudhury; April Torres; Shruti Gupta; Chris Kantorak; Tim Goble; Peter T Fox; Geoffrey D Clarke; Marcel M Daadi
Journal:  Stem Cells Transl Med       Date:  2016-09-22       Impact factor: 6.940

9.  Rapid inverse planning for pressure-driven drug infusions in the brain.

Authors:  Kathryn H Rosenbluth; Alastair J Martin; Stephan Mittermeyer; Jan Eschermann; Peter J Dickinson; Krystof S Bankiewicz
Journal:  PLoS One       Date:  2013-02-15       Impact factor: 3.240

10.  Effect of needle insertion speed on tissue injury, stress, and backflow distribution for convection-enhanced delivery in the rat brain.

Authors:  Fernando Casanova; Paul R Carney; Malisa Sarntinoranont
Journal:  PLoS One       Date:  2014-04-28       Impact factor: 3.240

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