| Literature DB >> 2118697 |
G Sirchia1, D Almini, A Bellobuono, A M Giovanetti, M Marconi, F Mercuriali, F Mozzi, A Parravicini, M Pizzi, F Zanuso.
Abstract
11,117 blood donors from 24 blood transfusion services evenly distributed throughout the various Italian regions were tested for the presence of hepatitis C virus (HCV) antibodies in the serum and serum alanine aminotransferase (ALT) level. The results are as follows: (1) anti-HCV seroprevalence in Italy was 0.87% with a difference between Northern and Southern regions (0.68 vs. 1.37%) and between younger and older subjects (0.62 vs. 1.21%); (2) prevalence of elevated ALT levels was 4.74% without a North-South effect (except than for markedly elevated ALT levels); (3) anti-HCV seroprevalence was higher in subjects with elevated ALT (5.0%), with a North-South effect (2.2 vs. 9.9%) and particularly high (19.2%) in subjects with markedly elevated ALT; (4) ALT levels were elevated in 26.2% of anti-HCV positive subjects, with a North-South effect (14 vs. 40.5%).Entities:
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Year: 1990 PMID： 2118697 DOI： 10.1111/j.1423-0410.1990.tb02109.x
Source DB: PubMed Journal: Vox Sang ISSN： 0042-9007 Impact factor: 2.144