Literature DB >> 2118572

Day-case surgery: enhanced recovery with flumazenil.

B R Birch1, K M Anson, E Clifford, R A Miller.   

Abstract

In an open, randomized, parallel group study of 84 adult patients undergoing elective day-case urological surgery the specific benzodiazepine antagonist flumazenil was shown to reverse effectively subjective postoperative sedation due to midazolam and enabled 83% of patients to recover and be ready for potential discharge within 15 min of surgery (control group 24% p less than 0.001). The significantly shorter recovery time has benefits in terms of increased patient cooperation and reduced demands on postoperative nursing care. The implications of these findings for day-case surgery are discussed.

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Year:  1990        PMID: 2118572      PMCID: PMC1292732          DOI: 10.1177/014107689008300709

Source DB:  PubMed          Journal:  J R Soc Med        ISSN: 0141-0768            Impact factor:   18.000


  10 in total

1.  Local anaesthesia for cataract surgery.

Authors:  S Rassam; H F Thomas
Journal:  Lancet       Date:  1989-01-14       Impact factor: 79.321

2.  Randomized clinical investigation of Ro 15-1788, a benzodiazepine antagonist, in reversing the central effects of flunitrazepam.

Authors:  S Jensen; L Kirkegaard; B N Anderson
Journal:  Eur J Anaesthesiol       Date:  1987-03       Impact factor: 4.330

3.  A survey of pre-operative fear.

Authors:  M A Ramsay
Journal:  Anaesthesia       Date:  1972-10       Impact factor: 6.955

4.  [A comparison of midazolam and diazepam for intramuscular premedication].

Authors:  Y Jullien; J Holzer; D Passeron; J du Cailar
Journal:  Ann Fr Anesth Reanim       Date:  1982

5.  The effect of Ro15-1788 (Anexate) on conscious sedation produced with midazolam.

Authors:  M R Rodrigo; J B Rosenquist
Journal:  Anaesth Intensive Care       Date:  1987-05       Impact factor: 1.669

6.  A study of intravenous sedation with diazepam and midazolam for dentistry in Hong Kong Chinese.

Authors:  M R Rodrigo; R N Clark
Journal:  Anaesth Intensive Care       Date:  1986-11       Impact factor: 1.669

7.  Comparison of midazolam, diazepam and placebo i.m. as premedication for regional anaesthesia. A randomized double-blind study.

Authors:  K Reinhart; G Dallinger-Stiller; R Dennhardt; G Heinemeyer; K Eyrich
Journal:  Br J Anaesth       Date:  1985-03       Impact factor: 9.166

8.  Intramuscular midazolam. A comparison of midazolam with papaveretum and hyoscine for intramuscular premedication.

Authors:  E J McAteer; J Dixon; J G Whitwam
Journal:  Anaesthesia       Date:  1984-12       Impact factor: 6.955

9.  Premedication with intramuscular midazolam: a prospective randomized double-blind controlled study.

Authors:  H R Vinik; J G Reves; D Wright
Journal:  Anesth Analg       Date:  1982-11       Impact factor: 5.108

10.  Selective antagonists of benzodiazepines.

Authors:  W Hunkeler; H Möhler; L Pieri; P Polc; E P Bonetti; R Cumin; R Schaffner; W Haefely
Journal:  Nature       Date:  1981-04-09       Impact factor: 49.962

  10 in total
  2 in total

1.  Medical or surgical orchidectomy.

Authors:  B R Birch
Journal:  BMJ       Date:  1991-04-27

Review 2.  Flumazenil. A reappraisal of its pharmacological properties and therapeutic efficacy as a benzodiazepine antagonist.

Authors:  R N Brogden; K L Goa
Journal:  Drugs       Date:  1991-12       Impact factor: 9.546

  2 in total

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