Literature DB >> 21185700

Electron arc therapy for bilateral chest wall irradiation: treatment planning and dosimetric study.

P K Sharma1, S V Jamema, K Kaushik, A Budrukkar, R Jalali, D D Deshpande, C M Tambe, R Sarin, A Munshi.   

Abstract

AIMS: The treatment of patients with synchronous bilateral breast cancer is a challenge. We present a report of dosimetric data of patients with bilateral chest walls as the target treated with electron arc therapy.
MATERIALS AND METHODS: Ten consecutive patients who had undergone electron arc therapy to the bilateral chest wall for breast cancer were analysed. After positioning and immobilisation, patients underwent computed tomography scans from the neck to the upper abdomen. Electron arc plans were generated using the PLATO RTS (V1.8.2 Nucletron) treatment planning system. Electron energy was chosen depending upon the depth and thickness of the planning target volume (PTV). For all patients, the arc angle ranged between 80 and 280° (start angle 80°, stop angle 280°). The homogeneity index, coverage index and doses to organs at risk were evaluated. The patient-specific output factor and thermoluminescence dosimetry (TLD) measurements were carried out for all patients. The total planned dose to the PTV was 50Gy/25 fractions/5 weeks.
RESULTS: The mean PTV (± standard deviation) was 568.9 (±116)cm(3). The mean PTV coverage was 89 (±5.8)% of the prescribed dose. For the right lung, the mean values of D(1) and D(10) were 46 (±7.6) and 30 (±9)Gy, respectively. For the left lung, the mean values of D(1) and D(10) were 45 (±7) and 27 (±8)Gy, respectively. For the heart, the mean values of D(1), D(5) and D(10) were 21 (±15), 13.5 (±12) and 9 (±9)Gy, respectively. The mean values of TLD at various pre-specified locations on the chest wall surface were 1.84, 1.82, 1.82, 1.89 and 1.78Gy, respectively
CONCLUSION: The electron arc technique for treating the bilateral chest wall is a feasible and pragmatic technique. This technique has the twin advantages of adequate coverage of the target volume and sparing of adjacent normal structures. However, compared with other techniques, it needs a firm quality assurance protocol for dosimetry and treatment delivery.
Copyright © 2010 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 21185700     DOI: 10.1016/j.clon.2010.09.005

Source DB:  PubMed          Journal:  Clin Oncol (R Coll Radiol)        ISSN: 0936-6555            Impact factor:   4.126


  3 in total

1.  Synchronous bilateral breast cancer irradiation: clinical and dosimetrical issues using volumetric modulated arc therapy and simultaneous integrated boost.

Authors:  Alba Fiorentino; Rosario Mazzola; Stefania Naccarato; Niccolò Giaj-Levra; Sergio Fersino; Gianluisa Sicignano; Umberto Tebano; Francesco Ricchetti; Ruggero Ruggieri; Filippo Alongi
Journal:  Radiol Med       Date:  2017-02-21       Impact factor: 3.469

2.  Use of tomotherapy in treatment of synchronous bilateral breast cancer: dosimetric comparison study.

Authors:  T Wadasadawala; B Visariya; R Sarin; R R Upreti; S Paul; R Phurailatpam
Journal:  Br J Radiol       Date:  2015-01-21       Impact factor: 3.039

3.  Volumetric modulated arc therapy for synchronous bilateral whole breast irradiation - A case study.

Authors:  Jan Seppälä; Janne Heikkilä; Kimmo Myllyoja; Kristiina Koskela
Journal:  Rep Pract Oncol Radiother       Date:  2015-06-15
  3 in total

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