Literature DB >> 21184391

[Delirium induced by drug treatment].

Christine Back1, Markus Wittmann, Ekkehard Haen.   

Abstract

Delirium may be induced by a variety of reasons, among them drugs and in particular the combination of drugs. In elderly people a delirium is often misinterpreted as dementia. Anticholinergic activity is the mode of action by which drugs cause delirium. Antipsychotic drugs, antidepressants, antihistamines, and of course anticholinergic drugs themselves are the major anticholinergic classes of drugs. In addition some opioids have anticholinergic effects. Other drugs may induce delirium by dehydration (loop diuretics like furosemide) or sedation (benzodiazapines like lorazepam). Elderly people are at especially high risk to develop delirium, because of the multitude of drugs often prescribed to them, because they tend to drink to little, and because their brain is more sensitive to psychoactive drugs.

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Year:  2011        PMID: 21184391     DOI: 10.1024/0040-5930/a000116

Source DB:  PubMed          Journal:  Ther Umsch        ISSN: 0040-5930


  2 in total

1.  Current use of anticholinergic medications in a large naturalistic sample of psychiatric patients.

Authors:  Sermin Toto; Gudrun Hefner; Martina Hahn; Christoph Hiemke; Sibylle C Roll; Jan Wolff; Ansgar Klimke
Journal:  J Neural Transm (Vienna)       Date:  2021-01-13       Impact factor: 3.575

2.  Potentially inappropriate medication in older psychiatric patients.

Authors:  Gudrun Hefner; Martina Hahn; Sermin Toto; Christoph Hiemke; Sibylle C Roll; Jan Wolff; Ansgar Klimke
Journal:  Eur J Clin Pharmacol       Date:  2020-10-08       Impact factor: 2.953

  2 in total

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