Literature DB >> 21184089

Control of cardiovascular differentiation by microRNAs.

Kisho Ohtani1, Stefanie Dimmeler.   

Abstract

MicroRNAs (miRs) are small non-coding RNAs, which control gene expression either by inducing mRNA degradation or by blocking translation, and play a crucial role in tissue homeostasis. In the cardiovascular system, miRs were shown to control cardiac hypertrophy, fibrosis and apoptosis, angiogenesis, and vessel remodeling. In addition, miRs regulate stem cell maintenance and some miRs induced cell fate decisions. This review summarizes the current insights into the control of stem cells and lineage commitment by miRs focusing specifically to the regulation of endothelial, smooth muscle, and cardiac lineage.

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Year:  2010        PMID： 21184089     DOI： 10.1007/s00395-010-0139-7

Source DB:  PubMed          Journal:  Basic Res Cardiol        ISSN： 0300-8428            Impact factor:   17.165


  46 in total

1.  Common variants in TGFBR2 and miR-518 genes are associated with hypertension in the Chinese population.

Authors:  Jinfeng Chen; Xianghai Zhao; Hairu Wang; Yanchun Chen; Wen Wang; Wei Zhou; Xuecai Wang; Junming Tang; Yanping Zhao; Xiangfeng Lu; Shufeng Chen; Laiyuan Wang; Chong Shen; Song Yang
Journal:  Am J Hypertens       Date:  2014-03-31       Impact factor: 2.689

Review 2.  Bone marrow mesenchymal stem cells for post-myocardial infarction cardiac repair: microRNAs as novel regulators.

Authors:  Zhuzhi Wen; Shaoxin Zheng; Changqing Zhou; Woliang Yuan; Jingfeng Wang; Tong Wang
Journal:  J Cell Mol Med       Date:  2012-04       Impact factor: 5.310

Review 3.  MicroRNAs as novel regulators of stem cell fate.

Authors:  Eunhyun Choi; Eunmi Choi; Ki-Chul Hwang
Journal:  World J Stem Cells       Date:  2013-10-26       Impact factor: 5.326

4.  Loss of MicroRNA-155 protects the heart from pathological cardiac hypertrophy.

Authors:  Hee Young Seok; Jinghai Chen; Masaharu Kataoka; Zhan-Peng Huang; Jian Ding; Jinglu Yan; Xiaoyun Hu; Da-Zhi Wang
Journal:  Circ Res       Date:  2014-03-21       Impact factor: 17.367

Review 5.  Molecular advances in reporter genes: the need to witness the function of stem cells in failing heart in vivo.

Authors:  Silvia Agostini; Fabio A Recchia; Vincenzo Lionetti
Journal:  Stem Cell Rev Rep       Date:  2012-06       Impact factor: 5.739

6.  E2F1-dependent miR-421 regulates mitochondrial fragmentation and myocardial infarction by targeting Pink1.

Authors:  Kun Wang; Lu-Yu Zhou; Jian-Xun Wang; Yin Wang; Teng Sun; Bing Zhao; Yong-Jie Yang; Tao An; Bo Long; Na Li; Cui-Yun Liu; Ying Gong; Jin-Ning Gao; Yan-Han Dong; Jian Zhang; Pei-Feng Li
Journal:  Nat Commun       Date:  2015-07-17       Impact factor: 14.919

7.  [New therapy concepts for heart failure with preserved ejection fraction].

Authors:  C Tschöpe; B Pieske
Journal:  Herz       Date:  2015-04       Impact factor: 1.443

Review 8.  Heart Failure with Preserved Ejection Fraction and Future Pharmacological Strategies: a Glance in the Crystal Ball.

Authors:  Carsten Tschöpe; Sophie Van Linthout; Behrouz Kherad
Journal:  Curr Cardiol Rep       Date:  2017-08       Impact factor: 2.931

9.  Epigenetics: an expanding new piece of the stroke puzzle.

Authors:  William J Pearce
Journal:  Transl Stroke Res       Date:  2011-09       Impact factor: 6.829

Review 10.  Emerging role of angiogenesis in adaptive and maladaptive right ventricular remodeling in pulmonary hypertension.

Authors:  Andrea L Frump; Sébastien Bonnet; Vinicio A de Jesus Perez; Tim Lahm
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2017-11-02       Impact factor: 5.464
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