BACKGROUND: in older people, induction of cutaneous vitamin D production by ultraviolet B (UVB) exposure may be preferable to oral supplementation: it cannot cause toxic levels, it helps to prevent polypharmacy and, moreover, there are indications that UVB exposure has beneficial effects on health and well being by mechanisms other than the vitamin D pathway alone. OBJECTIVE: the aim of this pilot study is to investigate whether weekly, half-body, UVB irradiation after showering can increase serum 25-hydroxyvitamin D (25(OH)D) to sufficient levels, in a Dutch psychogeriatric nursing home population. METHOD: subjects were eight psychogeriatric nursing home patients, mean age: 79 ± 8. Exclusion criteria were going outdoors into the sun more than once a week, the presence of actinic or cancer skin lesions and known resistance to body contact. The intervention consisted of weekly half-body UVB irradiation, after showering, over 8 weeks, with 0.5 minimal erythemal dose (MED). Main outcome measures were change in fasting serum levels of 25(OH)D and parathyroid hormone (PTH) at 0, 2, 4 and 8 weeks. RESULTS: at baseline, mean serum 25(OH)D was 28.5 nmol/l. Mean serum 25(OH)D levels increased to 46.5 nmol/l. Median serum PTH levels decreased by 20% after 8 weeks of treatment. CONCLUSION: an 8 week course of weekly, frontal half-body irradiation with UVB, at 0.5 MED, leads to an significant increase in 25(OH)D serum levels, but this period is too short to reach vitamin D sufficiency.
BACKGROUND: in older people, induction of cutaneous vitamin D production by ultraviolet B (UVB) exposure may be preferable to oral supplementation: it cannot cause toxic levels, it helps to prevent polypharmacy and, moreover, there are indications that UVB exposure has beneficial effects on health and well being by mechanisms other than the vitamin D pathway alone. OBJECTIVE: the aim of this pilot study is to investigate whether weekly, half-body, UVB irradiation after showering can increase serum 25-hydroxyvitamin D (25(OH)D) to sufficient levels, in a Dutch psychogeriatric nursing home population. METHOD: subjects were eight psychogeriatric nursing home patients, mean age: 79 ± 8. Exclusion criteria were going outdoors into the sun more than once a week, the presence of actinic or cancer skin lesions and known resistance to body contact. The intervention consisted of weekly half-body UVB irradiation, after showering, over 8 weeks, with 0.5 minimal erythemal dose (MED). Main outcome measures were change in fasting serum levels of 25(OH)D and parathyroid hormone (PTH) at 0, 2, 4 and 8 weeks. RESULTS: at baseline, mean serum 25(OH)D was 28.5 nmol/l. Mean serum 25(OH)D levels increased to 46.5 nmol/l. Median serum PTH levels decreased by 20% after 8 weeks of treatment. CONCLUSION: an 8 week course of weekly, frontal half-body irradiation with UVB, at 0.5 MED, leads to an significant increase in 25(OH)D serum levels, but this period is too short to reach vitamin D sufficiency.
Authors: Y Rolland; P de Souto Barreto; G Abellan Van Kan; C Annweiler; O Beauchet; H Bischoff-Ferrari; G Berrut; H Blain; M Bonnefoy; M Cesari; G Duque; M Ferry; O Guerin; O Hanon; B Lesourd; J Morley; A Raynaud-Simon; G Ruault; J-C Souberbielle; B Vellas Journal: J Nutr Health Aging Date: 2013-04 Impact factor: 4.075
Authors: Gustavo Duque; Stephen R Lord; Jenson Mak; Kirtan Ganda; Jacqueline J T Close; Peter Ebeling; Alexandra Papaioannou; Charles A Inderjeeth Journal: J Am Med Dir Assoc Date: 2016-06-24 Impact factor: 4.669
Authors: Victor Gm Chel; Marcel E Ooms; Jessie van der Bent; Fleur Veldkamp; Raymund Ac Roos; Wilco P Achterberg; Paul Lips Journal: Dermatoendocrinol Date: 2013-08-15
Authors: Jenna R Chalcraft; Linda M Cardinal; Perry J Wechsler; Bruce W Hollis; Kenneth G Gerow; Brenda M Alexander; Jill F Keith; D Enette Larson-Meyer Journal: Nutrients Date: 2020-07-27 Impact factor: 5.717