Literature DB >> 21183004

Improving Practices in US Hospitals to Prevent Venous Thromboembolism: lessons from ENDORSE.

Frederick A Anderson1, Samuel Z Goldhaber, Victor F Tapson, Jean-Francois Bergmann, Ajay K Kakkar, Bruno Deslandes, Wei Huang, Alexander T Cohen.   

Abstract

BACKGROUND: venous thromboembolism prophylaxis is suboptimal in the US despite long-standing evidence-based recommendations. The aim of this subset analysis of the Epidemiologic International Day for the Evaluation of Patients at Risk for Venous Thromboembolism in the Acute Hospital Care Setting (ENDORSE) study was to identify characteristics of hospitals with high guideline-recommended prophylaxis use.
METHODS: between September and November 2006, charts from eligible patients aged ≥ 40 years with an acute medical illness or age ≥ 18 years and undergoing a surgical procedure were reviewed from randomly selected US acute-care hospitals. Hospitals were ranked based on the proportion of at-risk patients who received American College of Chest Physicians-recommended types of prophylaxis. Hospital characteristics were compared to determine factors related to more frequent prophylaxis use. Hospitals were followed up 1 year after the chart audit.
RESULTS: overall, 9257 patients were evaluated from 81 hospitals. Appropriate types of prophylaxis were prescribed to more at-risk patients in hospitals in the highest quartile compared with the lowest quartile of prophylaxis use (74% vs 36%). All quartiles had a similar percentage of at-risk patients (61%-65%). Significantly more hospitals in the highest quartile had residency training programs (43% vs 5%), a larger median number of beds (277 vs 140), and had adopted hospital-wide prophylaxis protocols (76% vs 40%). In the follow-up survey, more hospitals overall had adopted hospital-wide written guidelines for venous thromboembolism prevention.
CONCLUSIONS: these findings support the value of hospital-wide protocols and local audits for VTE prevention, as recommended by several national quality-of-care groups. 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 21183004     DOI: 10.1016/j.amjmed.2010.07.011

Source DB:  PubMed          Journal:  Am J Med        ISSN: 0002-9343            Impact factor:   4.965


  7 in total

Review 1.  Benefits versus risks of pharmacological prophylaxis to prevent symptomatic venous thromboembolism in unselected medical patients revisited. Meta-analysis of the medical literature.

Authors:  Moshe Vardi; Michal Steinberg; Michal Haran; Shai Cohen
Journal:  J Thromb Thrombolysis       Date:  2012-07       Impact factor: 2.300

2.  Continuation of venous thromboembolism prophylaxis after hospital discharge into the outpatient setting: the ACCEPT study.

Authors:  Sebastian M Schellong; Jürgen Kaiser; Peter Bramlage
Journal:  J Thromb Thrombolysis       Date:  2015-02       Impact factor: 2.300

3.  National Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010).

Authors:  Karl E Minges; Behnood Bikdeli; Yun Wang; Nancy Kim; Jeptha P Curtis; Mayur M Desai; Harlan M Krumholz
Journal:  Am J Cardiol       Date:  2015-08-14       Impact factor: 2.778

4.  Current prevention practice for venous thromboembolism in Japanese intensive care units.

Authors:  Takeshi Yamamoto; Mashio Nakamura; Masayuki Kuroiwa; Keiji Tanaka
Journal:  J Anesth       Date:  2013-05-07       Impact factor: 2.078

5.  Venous Thromboembolism Risk and Adequacy of Prophylaxis in High Risk Pregnancy in the Arabian Gulf.

Authors:  Faisal Alsayegh; Waleed Al-Jassar; Salima Wani; Muna Tahlak; Awatef Albahar; Lamya Al Kharusi; Halima Al-Tamimi; Faten El-Taher; Naeema Mahmood; Ibrahim Al-Zakwani
Journal:  Curr Vasc Pharmacol       Date:  2016       Impact factor: 2.719

6.  Prophylaxis of venous thromboembolism in medical patients: too much or too little?

Authors:  Christian Fynbo Christiansen
Journal:  Clin Epidemiol       Date:  2012-11-15       Impact factor: 4.790

7.  Incidences and variations of hospital acquired venous thromboembolism in Australian hospitals: a population-based study.

Authors:  Hassan Assareh; Jack Chen; Lixin Ou; Ken Hillman; Arthas Flabouris
Journal:  BMC Health Serv Res       Date:  2016-09-22       Impact factor: 2.655

  7 in total

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