Literature DB >> 21181036

[Leprosy reactions in discharged patients following cure by multidrug therapy].

Linton Wallis Figueiredo Souza1.   

Abstract

INTRODUCTION: Reactional states are the main cause of nerve lesions and incapacities provoked by leprosy.
METHODS: Retrospective study aimed at verifying the frequency of leprosy reactions in discharged patients following cure by multidrug therapy (MDT).
RESULTS: Among patients who presented reactions during treatment, 35.5% continued after MDT; of those that did not present during treatment, only 12.7% presented after discharge; 63.4% multibacillary patients presented during and 31.7% after; 27.7% paucibacillary patients presented during and 8.3% after.
CONCLUSIONS: A direct proportional relation exists between the presence of reactions during and after treatment. Multibacillary clinical forms present a greater frequency of reactions during and after cure.

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Year:  2010        PMID: 21181036     DOI: 10.1590/s0037-86822010000600029

Source DB:  PubMed          Journal:  Rev Soc Bras Med Trop        ISSN: 0037-8682            Impact factor:   1.581


  7 in total

1.  Leprosy type-I reaction episode mimicking facial cellulitis--the importance of early diagnosis.

Authors:  Tania Rita Moreno de Oliveira Fernandes; Graziele Áquila de Souza Brandão; Bruno de Castro e Souza
Journal:  An Bras Dermatol       Date:  2015 May-Jun       Impact factor: 1.896

2.  Leprosy Reactions in Patients Coinfected with HIV: Clinical Aspects and Outcomes in Two Comparative Cohorts in the Amazon Region, Brazil.

Authors:  Carla Andréa Avelar Pires; Fernando Octávio Machado Jucá Neto; Nahima Castelo de Albuquerque; Geraldo Mariano Moraes Macedo; Keila de Nazaré Madureira Batista; Marília Brasil Xavier
Journal:  PLoS Negl Trop Dis       Date:  2015-06-01

Review 3.  Understanding the type 1 reactional state for early diagnosis and treatment: a way to avoid disability in leprosy.

Authors:  José Augusto da Costa Nery; Fred Bernardes Filho; Juliana Quintanilha; Alice Miranda Machado; Soraya de Souza Chantre Oliveira; Anna Maria Sales
Journal:  An Bras Dermatol       Date:  2013 Sep-Oct       Impact factor: 1.896

4.  Risk factors for physical disability in patients with leprosy disease in Yunnan, China: Evidence from a retrospective observational study.

Authors:  Xiaohua Chen; Hong-Bing Liu; Tie-Jun Shui; Shun Zha
Journal:  PLoS Negl Trop Dis       Date:  2021-11-10

Review 5.  Inflammatory Mediators of Leprosy Reactional Episodes and Dental Infections: A Systematic Review.

Authors:  D C B Cortela; A L de Souza Junior; M C L Virmond; E Ignotti
Journal:  Mediators Inflamm       Date:  2015-08-03       Impact factor: 4.711

6.  Leg ulcer in lepromatous leprosy - Case report.

Authors:  Tania Rita Moreno de Oliveira Fernandes; Talita Suzany Siqueira Dos Santos; Ramon Rodrigues de Macedo Lopes
Journal:  An Bras Dermatol       Date:  2016 Sep-Oct       Impact factor: 1.896

7.  Grade 2 disabilities in leprosy patients from Brazil: Need for follow-up after completion of multidrug therapy.

Authors:  Marcos Túlio Raposo; Martha Cerqueira Reis; Ana Virgínia de Queiroz Caminha; Jörg Heukelbach; Lucy Anne Parker; Maria Pastor-Valero; Maria Ines Battistella Nemes
Journal:  PLoS Negl Trop Dis       Date:  2018-07-16
  7 in total

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