Literature DB >> 21180608

Optimizing therapy with 6-mercaptopurine and azathioprine: to measure or not to measure?

Amar R Deshpande1, María T Abreu.   

Abstract

Entities:  

Year:  2010        PMID： 21180608      PMCID： PMC3002589          DOI： 10.1177/1756283X10376121

Source DB:  PubMed          Journal:  Therap Adv Gastroenterol        ISSN： 1756-283X            Impact factor:   4.409


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  23 in total

1.  Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy.

Authors:  J F Colombel; N Ferrari; H Debuysere; P Marteau; J P Gendre; B Bonaz; J C Soulé; R Modigliani; Y Touze; P Catala; C Libersa; F Broly
Journal:  Gastroenterology       Date:  2000-06       Impact factor: 22.682

Review 2.  The clinical pharmacology of 6-mercaptopurine.

Authors:  L Lennard
Journal:  Eur J Clin Pharmacol       Date:  1992       Impact factor: 2.953

3.  Controlled trial of azathioprine in Crohn's disease.

Authors:  J M Willoughby; J Beckett; P J Kumar; A M Dawson
Journal:  Lancet       Date:  1971-10-30       Impact factor: 79.321

4.  Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis.

Authors:  Mark T Osterman; Rabi Kundu; Gary R Lichtenstein; James D Lewis
Journal:  Gastroenterology       Date:  2006-04       Impact factor: 22.682

5.  Childhood leukaemia: a relationship between intracellular 6-mercaptopurine metabolites and neutropenia.

Authors:  L Lennard; C A Rees; J S Lilleyman; J L Maddocks
Journal:  Br J Clin Pharmacol       Date:  1983-10       Impact factor: 4.335

6.  Thiopurine methyltransferase activity influences clinical response to azathioprine in inflammatory bowel disease.

Authors:  Carmen Cuffari; Themistocles Dassopoulos; Lisa Turnbough; Richard E Thompson; Theodore M Bayless
Journal:  Clin Gastroenterol Hepatol       Date:  2004-05       Impact factor: 11.382

7.  Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity.

Authors:  R M Weinshilboum; S L Sladek
Journal:  Am J Hum Genet       Date:  1980-09       Impact factor: 11.025

8.  Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease.

Authors:  J Winter; A Walker; D Shapiro; D Gaffney; R J Spooner; P R Mills
Journal:  Aliment Pharmacol Ther       Date:  2004-09-15       Impact factor: 8.171

9.  CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.

Authors:  Imke Tiede; Gerhard Fritz; Susanne Strand; Daniela Poppe; Radovan Dvorsky; Dennis Strand; Hans Anton Lehr; Stefan Wirtz; Christoph Becker; Raja Atreya; Jonas Mudter; Kai Hildner; Brigitte Bartsch; Martin Holtmann; Richard Blumberg; Henning Walczak; Heiko Iven; Peter R Galle; Mohammad Reza Ahmadian; Markus F Neurath
Journal:  J Clin Invest       Date:  2003-04       Impact factor: 14.808

10.  Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations.

Authors:  L Lennard; J A Van Loon; J S Lilleyman; R M Weinshilboum
Journal:  Clin Pharmacol Ther       Date:  1987-01       Impact factor: 6.875
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  6 in total

Review 1.  Optimizing 6-mercaptopurine and azathioprine therapy in the management of inflammatory bowel disease.

Authors:  Kara Bradford; David Q Shih
Journal:  World J Gastroenterol       Date:  2011-10-07       Impact factor: 5.742

2.  Optimizing Thiopurine Therapy with a Xanthine Oxidase Inhibitor in Patients with Systemic Autoimmune Diseases: A Single-Centre Experience.

Authors:  Mériem Belhocine; Alissar Mourad; Aurélie Chapdelaine; Anne-Marie Mansour; Yves Troyanov; Maxime Doré
Journal:  Can J Hosp Pharm       Date:  2021

Review 3.  Thiopurine Therapy in Patients With Inflammatory Bowel Disease: A Focus on Metabolism and Pharmacogenetics.

Authors:  Ji Young Chang; Jae Hee Cheon
Journal:  Dig Dis Sci       Date:  2019-07-09       Impact factor: 3.487

4.  Harmful effects of the azathioprine metabolite 6-mercaptopurine in vascular cells: induction of mineralization.

Authors:  Jasmin Prüfer; Mirjam Schuchardt; Markus Tölle; Nicole Prüfer; Matthias Höhne; Walter Zidek; Markus van der Giet
Journal:  PLoS One       Date:  2014-07-16       Impact factor: 3.240

Review 5.  Thiopurine S-Methyltransferase as a Pharmacogenetic Biomarker: Significance of Testing and Review of Major Methods.

Authors:  Chingiz Asadov; Gunay Aliyeva; Kamala Mustafayeva
Journal:  Cardiovasc Hematol Agents Med Chem       Date:  2017-11-08

Review 6.  Review article: latent tuberculosis in patients with inflammatory bowel diseases receiving immunosuppression-risks, screening, diagnosis and management.

Authors:  Sasha R Fehily; Aysha H Al-Ani; Jonathan Abdelmalak; Clarissa Rentch; Eva Zhang; Justin T Denholm; Douglas Johnson; Siew C Ng; Vishal Sharma; David T Rubin; Peter R Gibson; Britt Christensen
Journal:  Aliment Pharmacol Ther       Date:  2022-05-20       Impact factor: 9.524
  6 in total

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