Literature DB >> 21179160

Drug discovery: Reader's block.

Sean D Taverna, Philip A Cole.   

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Year:  2010        PMID: 21179160     DOI: 10.1038/4681050a

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


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  11 in total

1.  Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains.

Authors:  Nicolas Reynoird; Brian E Schwartz; Manuela Delvecchio; Karin Sadoul; David Meyers; Chandrani Mukherjee; Cécile Caron; Hiroshi Kimura; Sophie Rousseaux; Philip A Cole; Daniel Panne; Christopher A French; Saadi Khochbin
Journal:  EMBO J       Date:  2010-07-30       Impact factor: 11.598

Review 2.  How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers.

Authors:  Sean D Taverna; Haitao Li; Alexander J Ruthenburg; C David Allis; Dinshaw J Patel
Journal:  Nat Struct Mol Biol       Date:  2007-11-05       Impact factor: 15.369

Review 3.  Chemical probes for histone-modifying enzymes.

Authors:  Philip A Cole
Journal:  Nat Chem Biol       Date:  2008-10       Impact factor: 15.040

4.  Chemical studies of histone acetylation. The occurrence of epsilon-N-acetyllysine in the f2a1 histone.

Authors:  E L Gershey; G Vidali; V G Allfrey
Journal:  J Biol Chem       Date:  1968-10-10       Impact factor: 5.157

Review 5.  Histone deacetylase inhibitors in the treatment of lymphoma.

Authors:  Manuela Lemoine; Anas Younes
Journal:  Discov Med       Date:  2010-11       Impact factor: 2.970

6.  Target structure-based discovery of small molecules that block human p53 and CREB binding protein association.

Authors:  Lois Resnick-Silverman; Sherry Yan; Shiraz Mutjaba; Wen-Jun Liu; Lei Zeng; James J Manfredi; Ming-Ming Zhou
Journal:  Chem Biol       Date:  2006-01

7.  Suppression of inflammation by a synthetic histone mimic.

Authors:  Edwige Nicodeme; Kate L Jeffrey; Uwe Schaefer; Soren Beinke; Scott Dewell; Chun-Wa Chung; Rohit Chandwani; Ivan Marazzi; Paul Wilson; Hervé Coste; Julia White; Jorge Kirilovsky; Charles M Rice; Jose M Lora; Rab K Prinjha; Kevin Lee; Alexander Tarakhovsky
Journal:  Nature       Date:  2010-11-10       Impact factor: 49.962

8.  Lysine acetylation targets protein complexes and co-regulates major cellular functions.

Authors:  Chunaram Choudhary; Chanchal Kumar; Florian Gnad; Michael L Nielsen; Michael Rehman; Tobias C Walther; Jesper V Olsen; Matthias Mann
Journal:  Science       Date:  2009-07-16       Impact factor: 47.728

9.  Cooperative binding of two acetylation marks on a histone tail by a single bromodomain.

Authors:  Jeanne Morinière; Sophie Rousseaux; Ulrich Steuerwald; Montserrat Soler-López; Sandrine Curtet; Anne-Laure Vitte; Jérôme Govin; Jonathan Gaucher; Karin Sadoul; Darren J Hart; Jeroen Krijgsveld; Saadi Khochbin; Christoph W Müller; Carlo Petosa
Journal:  Nature       Date:  2009-10-01       Impact factor: 49.962

10.  Selective inhibition of BET bromodomains.

Authors:  Panagis Filippakopoulos; Jun Qi; Sarah Picaud; Yao Shen; William B Smith; Oleg Fedorov; Elizabeth M Morse; Tracey Keates; Tyler T Hickman; Ildiko Felletar; Martin Philpott; Shonagh Munro; Michael R McKeown; Yuchuan Wang; Amanda L Christie; Nathan West; Michael J Cameron; Brian Schwartz; Tom D Heightman; Nicholas La Thangue; Christopher A French; Olaf Wiest; Andrew L Kung; Stefan Knapp; James E Bradner
Journal:  Nature       Date:  2010-09-24       Impact factor: 49.962

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  5 in total

1.  A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.

Authors:  Tonya M Gilbert; Stephen L McDaniel; Stephanie D Byrum; Jessica A Cades; Blair C R Dancy; Herschel Wade; Alan J Tackett; Brian D Strahl; Sean D Taverna
Journal:  Mol Cell Proteomics       Date:  2014-08-06       Impact factor: 5.911

2.  The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3.

Authors:  Anne M Cieniewicz; Linley Moreland; Alison E Ringel; Samuel G Mackintosh; Ana Raman; Tonya M Gilbert; Cynthia Wolberger; Alan J Tackett; Sean D Taverna
Journal:  Mol Cell Proteomics       Date:  2014-08-08       Impact factor: 5.911

3.  Drug discovery toward antagonists of methyl-lysine binding proteins.

Authors:  J Martin Herold; Lindsey A Ingerman; Cen Gao; Stephen V Frye
Journal:  Curr Chem Genomics       Date:  2011-08-22

4.  Open access target validation is a more efficient way to accelerate drug discovery.

Authors:  Wen Hwa Lee
Journal:  PLoS Biol       Date:  2015-06-04       Impact factor: 8.029

5.  Cytotoxic activity of bromodomain inhibitor NVS-CECR2-1 on human cancer cells.

Authors:  Seul Gi Park; Daye Lee; Hye-Ran Seo; Shin-Ai Lee; Jongbum Kwon
Journal:  Sci Rep       Date:  2020-10-01       Impact factor: 4.379

  5 in total

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