Literature DB >> 21178625

Advances in chronic obstructive pulmonary disease among older adults.

Christopher M Blanchette1, Susan R Berry, Sandi J Lane.   

Abstract

PURPOSE OF REVIEW: This review summarizes recent research on chronic obstructive pulmonary disease (COPD) among older adults. RECENT
FINDINGS: Recent research on COPD and older adults addresses four key areas: diagnosis and screening, comorbidities, end-of-life care, and management. These key findings include the Rotterdam study's identification of the incidence rate of COPD in older adults being 9.2 per 1000 person-years; a new assessment of FEV1 cut-points associated with increased prevalence of respiratory symptoms and risk of death; development and validation of new mortality scales, the ADO (age, dyspnea, and airflow obstruction) index and the PILE score; older adults with COPD average 9 comorbidities, of which depression, cardiovascular diseases such as hypertension, and chronic renal failure are highly prevalent; nonrespiratory treatments such as proton pump inhibitors, angiotensin-converting enzyme inhibitors, and statins show promise in the management of COPD; and strength may be a protective factor for older adults with COPD.
SUMMARY: Findings suggest that more research on older adults and COPD suggest that aging is a determinant of the progression of disease and that management of this population requires different metrics and strategies.

Entities:  

Mesh:

Year:  2011        PMID: 21178625     DOI: 10.1097/MCP.0b013e32834316ff

Source DB:  PubMed          Journal:  Curr Opin Pulm Med        ISSN: 1070-5287            Impact factor:   3.155


  8 in total

Review 1.  Rising Costs of COPD and the Potential for Maintenance Therapy to Slow the Trend.

Authors:  Christopher M Blanchette; Nicholas J Gross; Pablo Altman
Journal:  Am Health Drug Benefits       Date:  2014-04

Review 2.  Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype.

Authors:  Xu Chen; Xiaomao Xu; Fei Xiao
Journal:  Front Med       Date:  2013-12       Impact factor: 4.592

3.  Effects of comprehensive therapy based on traditional Chinese medicine patterns on older patients with chronic obstructive pulmonary disease: a subgroup analysis from a four-center, randomized, controlled study.

Authors:  Minghang Wang; Jiansheng Li; Suyun Li; Yang Xie
Journal:  Front Med       Date:  2014-09-09       Impact factor: 4.592

4.  Using cluster analysis to identify phenotypes and validation of mortality in men with COPD.

Authors:  Chiung-Zuei Chen; Liang-Yi Wang; Chih-Ying Ou; Cheng-Hung Lee; Chien-Chung Lin; Tzuen-Ren Hsiue
Journal:  Lung       Date:  2014-10-07       Impact factor: 2.584

5.  Suppressed expression of T-box transcription factors is involved in senescence in chronic obstructive pulmonary disease.

Authors:  George K Acquaah-Mensah; Deepti Malhotra; Madhulika Vulimiri; Jason E McDermott; Shyam Biswal
Journal:  PLoS Comput Biol       Date:  2012-07-19       Impact factor: 4.475

6.  Determinants of chronic obstructive pulmonary disease severity in the late-elderly differ from those in younger patients.

Authors:  Mizuha Haraguchi; Hidetoshi Nakamura; Mamoru Sasaki; Masaki Miyazaki; Shotaro Chubachi; Saeko Takahashi; Koichiro Asano; Paul W Jones; Tomoko Betsuyaku
Journal:  BMC Res Notes       Date:  2016-01-04

7.  Identification of Patient Profiles with High Risk of Hospital Re-Admissions for Acute COPD Exacerbations (AECOPD) in France Using a Machine Learning Model.

Authors:  Arnaud Cavailles; Boris Melloni; Stéphane Motola; Florent Dayde; Marie Laurent; Katell Le Lay; Didier Caumette; Laura Luciani; Pierre Louis Lleu; Geoffrey Berthon; Thomas Flament
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2020-04-30

Review 8.  The safety of long-acting β2-agonists in the treatment of stable chronic obstructive pulmonary disease.

Authors:  Marc L Decramer; Nicola A Hanania; Jan O Lötvall; Barbara P Yawn
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2013-01-25
  8 in total

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