BACKGROUND: The impact of chronic kidney disease (CKD) and hemodialysis on heart function is not fully understood. We aimed to investigate the influence of different stages of CKD and maintenance hemodialysis on heart function. METHODS: One hundred fifty-three patients were categorized into 3 subgroups [56 without CKD as controls; 37 with moderate-advanced CKD, stages 3, 4 or 5, and 60 with end-stage renal disease (ESRD) undergoing maintenance hemodialysis]. Left ventricular (LV) function was assessed by conventional echocardiography and 2-dimensional speckle-tracking echocardiography with strain analysis (2D strain analysis). RESULTS: There was no significant difference of gender, age and LV ejection fraction among groups. Compared with controls, global peak systolic longitudinal strain (GS(l)), circumferential strain and strain rate were decreased in the CKD group. Along with the decline of renal function, GS(l) deteriorated. Moreover, compared with moderate-advanced CKD patients, GS(l), circumferential strain and strain rate were better in ESRD group receiving maintenance hemodialysis. CONCLUSIONS: Worsening renal function was associated with a reduction of systolic function, and could be quantified by 2D strain analysis. The hemodialysis patients have better LV systolic function than the moderate-advanced CKD patients.
BACKGROUND: The impact of chronic kidney disease (CKD) and hemodialysis on heart function is not fully understood. We aimed to investigate the influence of different stages of CKD and maintenance hemodialysis on heart function. METHODS: One hundred fifty-three patients were categorized into 3 subgroups [56 without CKD as controls; 37 with moderate-advanced CKD, stages 3, 4 or 5, and 60 with end-stage renal disease (ESRD) undergoing maintenance hemodialysis]. Left ventricular (LV) function was assessed by conventional echocardiography and 2-dimensional speckle-tracking echocardiography with strain analysis (2D strain analysis). RESULTS: There was no significant difference of gender, age and LV ejection fraction among groups. Compared with controls, global peak systolic longitudinal strain (GS(l)), circumferential strain and strain rate were decreased in the CKD group. Along with the decline of renal function, GS(l) deteriorated. Moreover, compared with moderate-advanced CKDpatients, GS(l), circumferential strain and strain rate were better in ESRD group receiving maintenance hemodialysis. CONCLUSIONS: Worsening renal function was associated with a reduction of systolic function, and could be quantified by 2D strain analysis. The hemodialysis patients have better LV systolic function than the moderate-advanced CKDpatients.
Authors: Rafael Kramann; Johanna Erpenbeck; Rebekka K Schneider; Anna B Röhl; Marc Hein; Vincent M Brandenburg; Merel van Diepen; Friedo Dekker; Nicolaus Marx; Jürgen Floege; Michael Becker; Georg Schlieper Journal: J Am Soc Nephrol Date: 2014-04-03 Impact factor: 10.121
Authors: Ruth Lagies; Floris E A Udink Ten Cate; Markus Feldkötter; Bodo B Beck; Narayanswami Sreeram; Bernd Hoppe; Ulrike Herberg Journal: Pediatr Nephrol Date: 2019-08-22 Impact factor: 3.714
Authors: Attila Kovács; Mihály Tapolyai; Csilla Celeng; Edit Gara; Mária Faludi; Klára Berta; Astrid Apor; Andrea Nagy; András Tislér; Béla Merkely Journal: Int J Cardiovasc Imaging Date: 2014-07-08 Impact factor: 2.357