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Literature DB >> 21176729

Cytotoxic effects of opioids on cancer cell lines.

C Friesen¹, S Bacher, I Hormann, M Roscher, E Miltner.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2011 PMID： 21176729

Source DB: PubMed Journal: Int J Clin Pharmacol Ther ISSN： 0946-1965 Impact factor: 1.366

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3 in total

1. Overall Survival among Cancer Patients Undergoing Opioid Rotation to Methadone Compared to Other Opioids.

Authors: Akhila Reddy; Ulrich S Schuler; Maxine de la Cruz; Sriram Yennurajalingam; Jimin Wu; Diane Liu; Eduardo Bruera
Journal: J Palliat Med Date: 2016-12-20 Impact factor: 2.947

2. Methadone does not potentiate the effect of doxorubicin in canine tumour cell lines.

Authors: Claudia Cueni; Katarzyna J Nytko; Pauline Thumser-Henner; Mathias S Weyland; Carla Rohrer Bley
Journal: Vet Med Sci Date: 2020-04-19

3. D,L-Methadone causes leukemic cell apoptosis via an OPRM1-triggered increase in IP3R-mediated ER Ca²⁺ release and decrease in Ca²⁺ efflux, elevating [Ca²⁺]_i.

Authors: JungKwon Lee; Jesusa L Rosales; Hee-Guk Byun; Ki-Young Lee
Journal: Sci Rep Date: 2021-01-13 Impact factor: 4.379

3 in total

Cytotoxic effects of opioids on cancer cell lines.

1. Overall Survival among Cancer Patients Undergoing Opioid Rotation to Methadone Compared to Other Opioids.

2. Methadone does not potentiate the effect of doxorubicin in canine tumour cell lines.

3. D,L-Methadone causes leukemic cell apoptosis via an OPRM1-triggered increase in IP3R-mediated ER Ca2+ release and decrease in Ca2+ efflux, elevating [Ca2+]i.

3. D,L-Methadone causes leukemic cell apoptosis via an OPRM1-triggered increase in IP3R-mediated ER Ca²⁺ release and decrease in Ca²⁺ efflux, elevating [Ca²⁺]_i.