| Literature DB >> 21174473 |
Nicole M Deschamps1, Vassil I Elitzin, Bing Liu, Mark B Mitchell, Matthew J Sharp, Elie A Tabet.
Abstract
The triple reuptake inhibitor GSK1360707F was synthesized via an efficient and scalable route that features an enyne cycloisomerization reaction catalyzed by either Pt(II) or Au(I). Key aspects of this work such as the choice of the nitrogen protecting group and initial enantioselectivity studies are discussed.Entities:
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Year: 2010 PMID： 21174473 DOI： 10.1021/jo102098y
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354