Literature DB >> 21174393

An approach to the bis-oxazole macrocycle of diazonamides.

Jianmin Zhang1, Marco A Ciufolini.   

Abstract

A convergent approach to a macrocyclic compound embodying the complete "eastern" quadrant of diazonamides is described. The opening sequence in this work relies on an oxazole-forming reaction devised earlier in this group, while a late step involves a Robinson-Gabriel cyclization of an amidoketone to form a second oxazole.

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Year:  2010        PMID: 21174393     DOI: 10.1021/ol102678j

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  4 in total

1.  Room temperature copper(II)-catalyzed oxidative cyclization of enamides to 2,5-disubstituted oxazoles via vinylic C-H functionalization.

Authors:  Chi Wai Cheung; Stephen L Buchwald
Journal:  J Org Chem       Date:  2012-08-13       Impact factor: 4.354

2.  Catalyst-Free Synthesis of Polysubstituted 5-Acylamino-1,3-Thiazoles via Hantzsch Cyclization of α-Chloroglycinates.

Authors:  Mara Tomassetti; Gabriele Lupidi; Pamela Piermattei; Federico V Rossi; Samuele Lillini; Gianluca Bianchini; Andrea Aramini; Marco A Ciufolini; Enrico Marcantoni
Journal:  Molecules       Date:  2019-10-25       Impact factor: 4.411

3.  Synthesis of 2,5-diaryloxazoles through rhodium-catalyzed annulation of triazoles and aldehydes.

Authors:  Jian Li; Shang-Rong Zhu; Yue Xu; Xue-Chen Lu; Zheng-Bing Wang; Li Liu; De-Feng Xu
Journal:  RSC Adv       Date:  2020-06-30       Impact factor: 4.036

4.  Photochemical approach to functionalized benzobicyclo[3.2.1]octene structures via fused oxazoline derivatives from 4- and 5-(o-vinylstyryl)oxazoles.

Authors:  Ivana Sagud; Simona Božić; Zeljko Marinić; Marija Sindler-Kulyk
Journal:  Beilstein J Org Chem       Date:  2014-09-18       Impact factor: 2.883

  4 in total

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