Literature DB >> 21173910

Acute liver injury induced by weight-loss herbal supplements.

Gary C Chen1, Vivek S Ramanathan, David Law, Pauline Funchain, George C Chen, Samuel French, Boris Shlopov, Viktor Eysselein, David Chung, Sonya Reicher, Binh V Pham.   

Abstract

We report three cases of patients with acute liver injury induced by weight-loss herbal supplements. One patient took Hydroxycut while the other two took Herbalife supplements. Liver biopsies for all patients demonstrated findings consistent with drug-induced acute liver injury. To our knowledge, we are the first institute to report acute liver injury from both of these two types of weight-loss herbal supplements together as a case series. The series emphasizes the importance of taking a cautious approach when consuming herbal supplements for the purpose of weight loss.

Entities:  

Keywords:  Hepatotoxicity; Herbal; Herbalife; Hydroxycut; Weight-loss

Year:  2010        PMID: 21173910      PMCID: PMC3004035          DOI: 10.4254/wjh.v2.i11.410

Source DB:  PubMed          Journal:  World J Hepatol


  21 in total

Review 1.  Herbal remedies.

Authors:  Peter A G M De Smet
Journal:  N Engl J Med       Date:  2002-12-19       Impact factor: 91.245

2.  Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut.

Authors:  Tyler Stevens; Asif Qadri; Nizar N Zein
Journal:  Ann Intern Med       Date:  2005-03-15       Impact factor: 25.391

3.  Acute liver failure induced by green tea extracts: case report and review of the literature.

Authors:  Michele Molinari; Kymberly D S Watt; Thomas Kruszyna; Rebecca Nelson; Mark Walsh; Weei-Yuan Huang; Bjorn Nashan; Kevork Peltekian
Journal:  Liver Transpl       Date:  2006-12       Impact factor: 5.799

4.  [Hepatotoxicity associated with the consumption of herbal slimming products].

Authors:  José María Duque; José Ferreiro; Esther Salgueiro; Gloria Manso
Journal:  Med Clin (Barc)       Date:  2007-02-17       Impact factor: 1.725

5.  Acute liver injury associated with the herbal supplement hydroxycut in a soldier deployed to Iraq.

Authors:  Frances J Jones; Allan H Andrews
Journal:  Am J Gastroenterol       Date:  2007-10       Impact factor: 10.864

6.  Serious adverse liver reactions associated with herbal weight-loss supplements.

Authors:  E Bjornsson; Rolf Olsson
Journal:  J Hepatol       Date:  2007-05-29       Impact factor: 25.083

Review 7.  Bacillus subtilis as a cause of cholangitis in polycystic kidney and liver disease.

Authors:  F Wallet; V Crunelle; M Roussel-Delvallez; A Fruchart; P Saunier; R J Courcol
Journal:  Am J Gastroenterol       Date:  1996-07       Impact factor: 10.864

Review 8.  Hydroxycut hepatotoxicity: a case series and review of liver toxicity from herbal weight loss supplements.

Authors:  Lily Dara; Jennifer Hewett; Joseph Kartaik Lim
Journal:  World J Gastroenterol       Date:  2008-12-07       Impact factor: 5.742

9.  Severe hepatotoxicity following ingestion of Herbalife nutritional supplements contaminated with Bacillus subtilis.

Authors:  Felix Stickel; Sara Droz; Eleonora Patsenker; Katja Bögli-Stuber; Beat Aebi; Stephen L Leib
Journal:  J Hepatol       Date:  2008-10-18       Impact factor: 25.083

Review 10.  Supplemental products used for weight loss.

Authors:  Thomas L Lenz; William R Hamilton
Journal:  J Am Pharm Assoc (2003)       Date:  2004 Jan-Feb
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  16 in total

1.  A correction of misinformation regarding Herbalife.

Authors:  Kristy Appelhans; Raushanah Najeeullah; Vasilios Frankos
Journal:  World J Hepatol       Date:  2013-10-27

2.  Herbalife hepatotoxicity: Evaluation of cases with positive reexposure tests.

Authors:  Rolf Teschke; Christian Frenzel; Johannes Schulze; Alexander Schwarzenboeck; Axel Eickhoff
Journal:  World J Hepatol       Date:  2013-07-27

3.  Troxis necrosis, a novel mechanism for drug-induced hepatitis secondary to immunomodulatory therapy.

Authors:  Christina H Wei; Andrew Penunuri; George Karpouzas; Wayne Fleishman; Anuj Datta; Samuel W French
Journal:  Exp Mol Pathol       Date:  2015-08-20       Impact factor: 3.362

4.  Revisiting acute liver injury associated with herbalife products.

Authors:  Kristy Appelhans; Casey Smith; Ezra Bejar; Y Steve Henig
Journal:  World J Hepatol       Date:  2011-10-27

5.  An Investigation of Habitual Dietary Supplement Use Among 557 NCAA Division I Athletes.

Authors:  Michelle T Barrack; Mark Muster; Jennifer Nguyen; Aaron Rafferty; Terri Lisagor
Journal:  J Am Coll Nutr       Date:  2020-01-14       Impact factor: 3.169

6.  Weight Loss Supplements: Boon or Bane?

Authors:  Reshma Mohamed Ansari; Norfaizatul Shalida Omar
Journal:  Malays J Med Sci       Date:  2017-06-30

Review 7.  Acute liver injury following Garcinia cambogia weight-loss supplementation: case series and literature review.

Authors:  Giada Crescioli; Niccolò Lombardi; Alessandra Bettiol; Ettore Marconi; Filippo Risaliti; Michele Bertoni; Francesca Menniti Ippolito; Valentina Maggini; Eugenia Gallo; Fabio Firenzuoli; Alfredo Vannacci
Journal:  Intern Emerg Med       Date:  2018-05-25       Impact factor: 3.397

8.  A rare cause of drug-induced hepatitis in an immunocompromised patient and the role of glutathione.

Authors:  Viplove Senadhi; Deepika Arora; Manish Arora; Franklin Marsh
Journal:  World J Hepatol       Date:  2012-08-27

9.  What's new about inflammatory bowel diseases in Ischemic colitis induced by the newly reformulated multicomponent weight-loss supplement Hydroxycut(®).

Authors:  Muhammed Sherid; Salih Samo; Samian Sulaiman; Joseph H Gaziano
Journal:  World J Gastrointest Endosc       Date:  2013-04-16

Review 10.  Herbal hepatotoxicity in traditional and modern medicine: actual key issues and new encouraging steps.

Authors:  Rolf Teschke; Axel Eickhoff
Journal:  Front Pharmacol       Date:  2015-04-23       Impact factor: 5.810

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