Literature DB >> 21173802

Chaperoning the SNAREs: a role in preventing neurodegeneration?

Robert D Burgoyne, Alan Morgan.   

Abstract

Despite their potential importance as therapeutic targets, the initial events in neurodegenerative diseases are poorly understood. Emerging evidence suggests that presynaptic dysfunction might be an early event in these pathologies, and three papers now link dysregulation of SNAREprotein levels and function caused by the absence of synuclein or cysteine string protein (CSP) to activity-dependent neurodegeneration.

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Year:  2011        PMID： 21173802     DOI： 10.1038/ncb0111-8

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  18 in total

Review 1.  Tying everything together: the multiple roles of cysteine string protein (CSP) in regulated exocytosis.

Authors:  Gareth J O Evans; Alan Morgan; Robert D Burgoyne
Journal:  Traffic       Date:  2003-10       Impact factor: 6.215

2.  The synaptic vesicle protein CSP alpha prevents presynaptic degeneration.

Authors:  Rafael Fernández-Chacón; Markus Wölfel; Hiroshi Nishimune; Lucia Tabares; Frank Schmitz; Manuel Castellano-Muñoz; Christian Rosenmund; Maria L Montesinos; Joshua R Sanes; Ralf Schneggenburger; Thomas C Südhof
Journal:  Neuron       Date:  2004-04-22       Impact factor: 17.173

Review 3.  A century-old debate on protein aggregation and neurodegeneration enters the clinic.

Authors:  Peter T Lansbury; Hilal A Lashuel
Journal:  Nature       Date:  2006-10-19       Impact factor: 49.962

4.  A charged prominence in the linker domain of the cysteine-string protein Cspα mediates its regulated interaction with the calcium sensor synaptotagmin 9 during exocytosis.

Authors:  Frédéric Boal; Michel Laguerre; Alexandra Milochau; Jochen Lang; Pier A Scotti
Journal:  FASEB J       Date:  2010-09-16       Impact factor: 5.191

5.  A cysteine-string protein is expressed in retina and brain of Drosophila.

Authors:  K E Zinsmaier; A Hofbauer; G Heimbeck; G O Pflugfelder; S Buchner; E Buchner
Journal:  J Neurogenet       Date:  1990-11       Impact factor: 1.250

6.  CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity.

Authors:  Manu Sharma; Jacqueline Burré; Thomas C Südhof
Journal:  Nat Cell Biol       Date:  2010-12-12       Impact factor: 28.824

7.  Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration.

Authors:  Sreeganga Chandra; Gilbert Gallardo; Rafael Fernández-Chacón; Oliver M Schlüter; Thomas C Südhof
Journal:  Cell       Date:  2005-11-04       Impact factor: 41.582

8.  Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology.

Authors:  Bryony C Gray; Zuzana Siskova; V Hugh Perry; Vincent O'Connor
Journal:  Neurobiol Dis       Date:  2009-04-10       Impact factor: 5.996

9.  Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.

Authors:  Jacqueline Burré; Manu Sharma; Theodoros Tsetsenis; Vladimir Buchman; Mark R Etherton; Thomas C Südhof
Journal:  Science       Date:  2010-08-26       Impact factor: 47.728

10.  Presenilins are essential for regulating neurotransmitter release.

Authors:  Chen Zhang; Bei Wu; Vassilios Beglopoulos; Mary Wines-Samuelson; Dawei Zhang; Ioannis Dragatsis; Thomas C Südhof; Jie Shen
Journal:  Nature       Date:  2009-07-30       Impact factor: 49.962
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  27 in total

Review 1.  GPCR mediated regulation of synaptic transmission.

Authors:  Katherine M Betke; Christopher A Wells; Heidi E Hamm
Journal:  Prog Neurobiol       Date:  2012-01-28       Impact factor: 11.685

2.  The Gos28 SNARE protein mediates intra-Golgi transport of rhodopsin and is required for photoreceptor survival.

Authors:  Erica E Rosenbaum; Eva Vasiljevic; Spencer C Cleland; Carlos Flores; Nansi Jo Colley
Journal:  J Biol Chem       Date:  2014-09-26       Impact factor: 5.157

3.  Mutations in DNAJC5, encoding cysteine-string protein alpha, cause autosomal-dominant adult-onset neuronal ceroid lipofuscinosis.

Authors:  Lenka Nosková; Viktor Stránecký; Hana Hartmannová; Anna Přistoupilová; Veronika Barešová; Robert Ivánek; Helena Hůlková; Helena Jahnová; Julie van der Zee; John F Staropoli; Katherine B Sims; Jaana Tyynelä; Christine Van Broeckhoven; Peter C G Nijssen; Sara E Mole; Milan Elleder; Stanislav Kmoch
Journal:  Am J Hum Genet       Date:  2011-08-04       Impact factor: 11.025

Review 4.  Advances in the genetics of Parkinson disease.

Authors:  Joanne Trinh; Matt Farrer
Journal:  Nat Rev Neurol       Date:  2013-07-16       Impact factor: 42.937

5.  Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation.

Authors:  Minglei Zhao; Duilio Cascio; Michael R Sawaya; David Eisenberg
Journal:  Protein Sci       Date:  2011-05-03       Impact factor: 6.725

Review 6.  Gene expression profiling in the human alcoholic brain.

Authors:  Anna S Warden; R Dayne Mayfield
Journal:  Neuropharmacology       Date:  2017-03-15       Impact factor: 5.250

Review 7.  The yin and yang of amyloid: insights from α-synuclein and repeat domain of Pmel17.

Authors:  Ryan P McGlinchey; Thai Leong Yap; Jennifer C Lee
Journal:  Phys Chem Chem Phys       Date:  2011-10-12       Impact factor: 3.676

8.  SNAP-25 is abundantly expressed in enteric neuronal networks and upregulated by the neurotrophic factor GDNF.

Authors:  M Barrenschee; M Böttner; J Harde; C Lange; F Cossais; M Ebsen; I Vogel; T Wedel
Journal:  Histochem Cell Biol       Date:  2015-02-06       Impact factor: 4.304

9.  Proteome Analysis of Potential Synaptic Vesicle Cycle Biomarkers in the Cerebrospinal Fluid of Patients with Sporadic Creutzfeldt-Jakob Disease.

Authors:  Chunyu Wang; Deming Zhao; Syed Zahid Ali Shah; Wei Yang; Chaosi Li; Lifeng Yang
Journal:  Mol Neurobiol       Date:  2016-08-25       Impact factor: 5.590

10.  Is Parkinson's disease a lysosomal disorder?

Authors:  Andrés D Klein; Joseph R Mazzulli
Journal:  Brain       Date:  2018-08-01       Impact factor: 13.501
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