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Literature DB >> 21173179

Complete nucleotide sequence of plasmid pTN48, encoding the CTX-M-14 extended-spectrum β-lactamase from an Escherichia coli O102-ST405 strain.

Typhaine Billard-Pomares¹, Olivier Tenaillon, Hervé Le Nagard, Zoé Rouy, Stéphane Cruveiller, Claudine Médigue, Guillaume Arlet, Erick Denamur, Catherine Branger.

Abstract

The sequence of pTN48, a plasmid of the FII-FIB replicon type that encodes a CTX-M-14 enzyme in an Escherichia coli strain of the phylogenetic group D₂ O102-ST405 clone, was determined. pTN48 is, for the most part, a mosaic of virulence, antibiotic resistance, and addiction system modules found in various other plasmids. The presence of multiple addiction systems indicates that the plasmid should be stably maintained in the E. coli clone, favoring dissemination of the CTX-M-14 enzyme.

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Year: 2010 PMID： 21173179 PMCID： PMC3067099 DOI： 10.1128/AAC.01108-10

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

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