Literature DB >> 21172649

Targeted ubiquitylation: the prey becomes predator.

Jun Yan1, Yue Xiong.   

Abstract

Being targeted for polyubiquitylation often means the end of life for the substrate protein. In this issue of Molecular Cell, Ouni et al. (2010) demonstrate that the yeast transcription factor Met4, a target of the SCF(Met30) E3 ligase for nonproteolytic polyubiquitylation, can also function to target its cofactors for proteolytic ubiquitylation by the same E3 ligase.
Copyright © 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID： 21172649      PMCID： PMC3232680          DOI： 10.1016/j.molcel.2010.12.012

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  8 in total

1.  Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4.

Authors:  P Kaiser; K Flick; C Wittenberg; S I Reed
Journal:  Cell       Date:  2000-08-04       Impact factor: 41.582

2.  Inducible dissociation of SCF(Met30) ubiquitin ligase mediates a rapid transcriptional response to cadmium.

Authors:  Régine Barbey; Peggy Baudouin-Cornu; Traci A Lee; Astrid Rouillon; Patrick Zarzov; Mike Tyers; Dominique Thomas
Journal:  EMBO J       Date:  2005-01-20       Impact factor: 11.598

3.  A ubiquitin-interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome.

Authors:  Karin Flick; Shahri Raasi; Hongwei Zhang; James L Yen; Peter Kaiser
Journal:  Nat Cell Biol       Date:  2006-04-09       Impact factor: 28.824

4.  Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase.

Authors:  Bing Hao; Ning Zheng; Brenda A Schulman; Geng Wu; Julie J Miller; Michele Pagano; Nikola P Pavletich
Journal:  Mol Cell       Date:  2005-10-07       Impact factor: 17.970

5.  SCF(Met30)-mediated control of the transcriptional activator Met4 is required for the G(1)-S transition.

Authors:  E E Patton; C Peyraud; A Rouillon; Y Surdin-Kerjan; M Tyers; D Thomas
Journal:  EMBO J       Date:  2000-04-03       Impact factor: 11.598

6.  Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome.

Authors:  R E Kiernan; S Emiliani; K Nakayama; A Castro; J C Labbé; T Lorca; K Nakayama Ki; M Benkirane
Journal:  Mol Cell Biol       Date:  2001-12       Impact factor: 4.272

Review 7.  Metabolism of sulfur amino acids in Saccharomyces cerevisiae.

Authors:  D Thomas; Y Surdin-Kerjan
Journal:  Microbiol Mol Biol Rev       Date:  1997-12       Impact factor: 11.056

8.  TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex.

Authors:  Yu Tian; Robert Kolb; Jeong-Ho Hong; John Carroll; Dawei Li; John You; Roderick Bronson; Michael B Yaffe; Jing Zhou; Thomas Benjamin
Journal:  Mol Cell Biol       Date:  2007-07-16       Impact factor: 4.272
  8 in total
  3 in total

1.  Regulation and function of the TAZ transcription co-activator.

Authors:  Chenying Liu; Wei Huang; Qunying Lei
Journal:  Int J Biochem Mol Biol       Date:  2011-07-20

2.  Ubiquitin and transcription: The SCF/Met4 pathway, a (protein-) complex issue.

Authors:  Ikram Ouni; Karin Flick; Peter Kaiser
Journal:  Transcription       Date:  2011-05

Review 3.  Lipid transport between the endoplasmic reticulum and mitochondria.

Authors:  Vid V Flis; Günther Daum
Journal:  Cold Spring Harb Perspect Biol       Date:  2013-06-01       Impact factor: 10.005
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.