BACKGROUND: The association between ulcerative colitis and thyroid disorders has been previously reported. However, most reports consist of single case description, and a systematic assessment of this relationship has only sporadically been investigated. AIMS: To study a cohort of patients with ulcerative colitis to establish the prevalence of hyper- and hypothyroidism. MATERIAL AND METHODS: During a four-year period, we studied thyroid function in 162 ulcerative colitis patients (62 men, 100 women, age range 18-78 years). RESULTS: Thyroid dysfunction was present in 4 patients (2.5%) of the overall population and was represented by both hypo- (3 patients) and hyperthyroidism (1 patient). The incidence of this kind of thyroid dysfunction was significantly (p=0.03) lower than that found in a large (more than 5000 subjects) control group. CONCLUSIONS: We conclude that the prevalence of hyper-/hypothyroidism is relatively low in patients with ulcerative colitis, at least in our country, and does not justify a systematic investigation of the thyroid function, except in selected cases, probably those with scarce or no response to standard therapeutic measures.
BACKGROUND: The association between ulcerative colitis and thyroid disorders has been previously reported. However, most reports consist of single case description, and a systematic assessment of this relationship has only sporadically been investigated. AIMS: To study a cohort of patients with ulcerative colitis to establish the prevalence of hyper- and hypothyroidism. MATERIAL AND METHODS: During a four-year period, we studied thyroid function in 162 ulcerative colitispatients (62 men, 100 women, age range 18-78 years). RESULTS:Thyroid dysfunction was present in 4 patients (2.5%) of the overall population and was represented by both hypo- (3 patients) and hyperthyroidism (1 patient). The incidence of this kind of thyroid dysfunction was significantly (p=0.03) lower than that found in a large (more than 5000 subjects) control group. CONCLUSIONS: We conclude that the prevalence of hyper-/hypothyroidism is relatively low in patients with ulcerative colitis, at least in our country, and does not justify a systematic investigation of the thyroid function, except in selected cases, probably those with scarce or no response to standard therapeutic measures.
Authors: Oskar Kornasiewicz; Marcin Dębski; Michal Grat; Barbara Lenartowicz; Marta Stępnowska; Anna Szałas; Ewa Bar-Andziak; Marek Krawczyk Journal: Arch Med Sci Date: 2013-08-20 Impact factor: 3.318
Authors: Simeng Lin; Neil Chanchlani; Isabel Carbery; Malik Janjua; Rachel Nice; Timothy J McDonald; Claire Bewshea; Nicholas A Kennedy; Tariq Ahmad; Christian P Selinger; James R Goodhand Journal: Aliment Pharmacol Ther Date: 2022-06-29 Impact factor: 9.524
Authors: Aleksandra Furtak; Anna Maria Wedrychowicz; Malgorzata Sladek; Andrzej Wedrychowicz; Krzysztof Fyderek; Jerzy Starzyk Journal: Front Endocrinol (Lausanne) Date: 2020-09-15 Impact factor: 5.555