Literature DB >> 21172189

Limited ileo-caecal resection for localised Crohn's disease in childhood: Clinical outcome and predictors of further surgery.

L Cook1, E Al-Hendawi, A W Bates, M Brennan, C Salvestrini, M Malik, F Torrente, O Ogunbiyi, A Lewis, R B Heuschkel.   

Abstract

OBJECTIVES: To investigate the outcome of limited ileo-caecal resection in children with localised Crohn's disease (CD) and determine predictors of further surgery.
METHODS: Review of children diagnosed with CD and operated on for ileo-caecal disease from 1995 to 2005. Age at diagnosis, endoscopic disease distribution, indication for surgery, site of recurrence and date of last follow-up were recorded. Surgery required removal of only the ileo-caecal junction and caecal pole with removal of the minimum terminal ileal length.
RESULTS: Thirty seven children underwent intestinal resection. Time between primary operation and most recent follow-up was 3.8 years (range 1 month-8.8 years). Indications for surgery were obstruction/stricture (20), treatment-resistant disease (13) and abscess/perforation peritonitis (4). Follow-up was available in 32. Nine (28%) required re-laparotomy. Median time to second laparotomy was 12 months (range 4-58 months). Eighteen children required no endoscopies after surgery (median follow-up 3.4 years).
CONCLUSION: Most conservative surgery occurs about 2 years after diagnosis. About 1 in 4 children have a further laparotomy within 12 months. Over half of these require division of adhesions. Limited ileo-caecal resection for localized Crohn's disease is not associated with early peri-anastomotic recurrence. Developments in laparoscopic surgery are likely to further reduce complications from adhesions.

Entities:  

Year:  2007        PMID: 21172189     DOI: 10.1016/j.crohns.2007.08.003

Source DB:  PubMed          Journal:  J Crohns Colitis        ISSN: 1873-9946            Impact factor:   9.071


  1 in total

1.  Does Ileocecal Resection Affect Children's Medium-Long-Term Growth and Defecation Patterns? A Matched Case-Control Study.

Authors:  Jiayu Yan; Waiun Lei; Yajun Chen
Journal:  J Gastrointest Surg       Date:  2022-06-01       Impact factor: 3.267

  1 in total

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