Literature DB >> 2117173

Management of chronic airway obstruction: theophylline--is it still necessary?

D Ukena1, G W Sybrecht.   

Abstract

Theophylline is a second-line drug for the symptomatic treatment of obstructive pulmonary diseases. It appears to be of particular value in the treatment of the more severe cases of airway obstruction. The likelihood of a therapeutic benefit and the safety of drug therapy can be increased markedly by an individually optimized theophylline therapy, that is, individual dosage and time of dosing, and monitoring the serum concentrations.

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Year:  1990        PMID： 2117173     DOI： 10.1007/bf02718187

Source DB:  PubMed          Journal:  Lung        ISSN： 0341-2040            Impact factor:   2.584


  22 in total

1.  Diaphragmatic fatigue in man.

Authors:  C S Roussos; P T Macklem
Journal:  J Appl Physiol Respir Environ Exerc Physiol       Date:  1977-08

2.  Effect of aminophylline on respiratory center activity and metabolic rate in premature infants with idiopathic apnea.

Authors:  T Gerhardt; J McCarthy; E Bancalari
Journal:  Pediatrics       Date:  1979-04       Impact factor: 7.124

3.  Apnoeic attacks in the newborn treated with aminophylline.

Authors:  J A Kuzemko; J Paala
Journal:  Arch Dis Child       Date:  1973-05       Impact factor: 3.791

Review 4.  The pharmacology and therapeutic use of theophylline.

Authors:  M Weinberger
Journal:  J Allergy Clin Immunol       Date:  1984-05       Impact factor: 10.793

5.  Theophylline has a dose-related effect on the airway response to inhaled histamine and methacholine in asthmatics.

Authors:  H Magnussen; G Reuss; R Jörres
Journal:  Am Rev Respir Dis       Date:  1987-11

Review 6.  The use of theophylline in 'irreversible' chronic obstructive pulmonary disease. An update.

Authors:  N S Hill
Journal:  Arch Intern Med       Date:  1988-12

7.  Inhaled corticosteroids reduce the severity of bronchial hyperresponsiveness in asthma but oral theophylline does not.

Authors:  J I Dutoit; C M Salome; A J Woolcock
Journal:  Am Rev Respir Dis       Date:  1987-11

8.  Theophylline reduces the response to nasal challenge with antigen.

Authors:  R M Naclerio; D Bartenfelder; D Proud; A G Togias; D A Meyers; A Kagey-Sobotka; P S Norman; L M Lichtenstein
Journal:  Am J Med       Date:  1985-12-20       Impact factor: 4.965

9.  The efficacy of orally administered theophylline, inhaled salbutamol, and a combination of the two as chronic therapy in the management of chronic bronchitis with reversible air-flow obstruction.

Authors:  D R Taylor; B Buick; C Kinney; R C Lowry; D G McDevitt
Journal:  Am Rev Respir Dis       Date:  1985-05

10.  Nocturnal asthma therapy. Inhaled bitolterol versus sustained-release theophylline.

Authors:  C W Zwillich; S R Neagley; L Cicutto; D P White; R J Martin
Journal:  Am Rev Respir Dis       Date:  1989-02
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  2 in total

1.  Influence of a potential anti-asthmatic drug, CR 2039, upon the anticonvulsive activity of conventional antiepileptics against maximal electroshock-induced seizures in mice.

Authors:  S J Czuczwar; M Gasior; M Kozicka; T Pietrasiewicz; W A Turski; Z Kleinrok
Journal:  J Neural Transm (Vienna)       Date:  1996       Impact factor: 3.575

2.  Anticonvulsant activity of carbamazepine and diphenylhydantoin against maximal electroshock in mice chronically treated with aminophylline.

Authors:  P Wlaź; Z Roliński; Z Kleinrok; S J Czuczwar
Journal:  J Neural Transm Gen Sect       Date:  1992
  2 in total

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