Literature DB >> 2117172

Mucolytics: when dispensable, when necessary?

P Dorow1.   

Abstract

Many patients with chest disease have difficulty in clearing their chests of sputum. A variety of substances have been used in an attempt to help them. Mucolytic drugs can alter the rheological properties of mucus by acting directly on the secretions or by modifying the metabolic activity of the mucus secreting cells. Many physicians and patients are certain to reap a benefit. This paper will discuss the effectiveness of mucolytic therapy.

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Year:  1990        PMID: 2117172     DOI: 10.1007/bf02718186

Source DB:  PubMed          Journal:  Lung        ISSN: 0341-2040            Impact factor:   2.584


  8 in total

1.  The reduction in vitro in viscosity of mucoprotein solutions by a new mucolytic agent, N-acetyl-L-cysteine.

Authors:  A L SHEFFNER
Journal:  Ann N Y Acad Sci       Date:  1963-03-30       Impact factor: 5.691

2.  Effect of N-acetylcysteine in subjects with slow pulmonary mucociliary clearance.

Authors:  T Todisco; R Polidori; F Rossi; L Iannacci; B Bruni; L Fedeli; R Palumbo
Journal:  Eur J Respir Dis Suppl       Date:  1985

3.  Effect of oral N-acetylcysteine on mucus clearance.

Authors:  A B Millar; D Pavia; J E Agnew; M T Lopez-Vidriero; D Lauque; S W Clarke
Journal:  Br J Dis Chest       Date:  1985-07

4.  Long-term home use of acetylcysteine in chronic bronchitis.

Authors:  S Chodosh; W Baigelman; T C Medici; K Enslein
Journal:  Curr Ther Res Clin Exp       Date:  1975-04

5.  Acetylcysteine in chronic bronchitis.

Authors:  S Chodosh
Journal:  Eur J Respir Dis Suppl       Date:  1980

6.  A controlled study of the safety and efficacy of acetylcysteine-isoproterenol combination.

Authors:  D F Pulle; P Glass; M J Dulfano
Journal:  Curr Ther Res Clin Exp       Date:  1970-08

7.  No penetration of orally administered N-acetylcysteine into bronchoalveolar lavage fluid.

Authors:  I A Cotgreave; A Eklund; K Larsson; P W Moldéus
Journal:  Eur J Respir Dis       Date:  1987-02

8.  Oral acetylcysteine reduces exacerbation rate in chronic bronchitis: report of a trial organized by the Swedish Society for Pulmonary Diseases.

Authors:  G Boman; U Bäcker; S Larsson; B Melander; L Wåhlander
Journal:  Eur J Respir Dis       Date:  1983-08
  8 in total

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