Literature DB >> 2117063

State analysis of endogenous cyanate ion in human plasma.

I Koshiishi1, T Imanari.   

Abstract

Cyanate ion is continuously produced by spontaneous degradation of urea both in healthy human blood and in blood of patients with uremia on intermittent hemodialysis. The cyanate ion is trapped irreversibly by amino groups as N-carbamyl groups and reversibly by sulfhydryl groups as S-carbamyl groups. Consequently, these reactions keep the cyanate ion levels in plasma extremely low. Plasma proteins may play an important role in the detoxication of cyanate ion.

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Year:  1990        PMID： 2117063     DOI： 10.1248/bpb1978.13.254

Source DB:  PubMed          Journal:  J Pharmacobiodyn        ISSN： 0386-846X


  3 in total

Review 1.  Mechanisms and consequences of carbamoylation.

Authors:  Sigurd Delanghe; Joris R Delanghe; Reinhart Speeckaert; Wim Van Biesen; Marijn M Speeckaert
Journal:  Nat Rev Nephrol       Date:  2017-07-31       Impact factor: 28.314

Review 2.  The Role of Posttranslational Protein Modifications in Rheumatological Diseases: Focus on Rheumatoid Arthritis.

Authors:  Andrea Mastrangelo; Tania Colasanti; Cristiana Barbati; Arbi Pecani; Danilo Sabatinelli; Monica Pendolino; Simona Truglia; Laura Massaro; Riccardo Mancini; Francesca Miranda; Francesca Romana Spinelli; Fabrizio Conti; Cristiano Alessandri
Journal:  J Immunol Res       Date:  2015-05-18       Impact factor: 4.818

3.  Carbamylated albumin is one of the target antigens of anti-carbamylated protein antibodies.

Authors:  Shuichiro Nakabo; Motomu Hashimoto; Shinji Ito; Moritoshi Furu; Hiromu Ito; Takao Fujii; Hajime Yoshifuji; Yoshitaka Imura; Ran Nakashima; Kosaku Murakami; Nobuo Kuramoto; Masao Tanaka; Junko Satoh; Akihito Ishigami; Satoshi Morita; Tsuneyo Mimori; Koichiro Ohmura
Journal:  Rheumatology (Oxford)       Date:  2017-07-01       Impact factor: 7.580
  3 in total

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