Literature DB >> 2116956

Are accessory molecules implicated in activation of T cells at the blood-retinal barrier?

J Liversidge1, J V Forrester.   

Abstract

Co-culture of rat retinal pigment epithelial (RPE) cells or retinal capillary endothelial (EC) cells with T lymphocytes from immunised syngeneic rats indicated that RPE cells but not EC could process retinal S-antigen and induce antigen specific T cell activation. Activation of lymphocytes by EC however was also antigen independent, and may be due to T cell (CD2) endothelial cell (LFA-3) ligand interactions which are functional on EC but not RPE.

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Year:  1990        PMID: 2116956     DOI: 10.3109/02713689008999432

Source DB:  PubMed          Journal:  Curr Eye Res        ISSN: 0271-3683            Impact factor:   2.424


  2 in total

1.  Immune response to specific molecules of the retina in proliferative vitreoretinal disorders.

Authors:  S Grisanti; K Heimann; P Wiedemann
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1994-05       Impact factor: 3.117

2.  Microglia in the mouse retina alter the structure and function of retinal pigmented epithelial cells: a potential cellular interaction relevant to AMD.

Authors:  Wenxin Ma; Lian Zhao; Aurora M Fontainhas; Robert N Fariss; Wai T Wong
Journal:  PLoS One       Date:  2009-11-20       Impact factor: 3.240

  2 in total

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