Literature DB >> 21169139

Antimicrobial activity of some synthesized glucopyranosyl-pyrimidine carbonitrile and fused pyrimidine systems.

Hayam H Sayed1, Hebat-Allah S Abbas, Eman M H Morsi, Abd El-Galil E Amr, Nayera A M Abdelwahad.   

Abstract

3-Amino-5-(4-chlorophenylamino)-4-cyanofuran-2-carboxamide (2) was used as the key molecule for preparation of various furopyrimidines 3-9 and formation of spiro-cycloalkane furopyrimidines 10, 11. Also, poly fused heterocyclic compounds 13-17 were prepared from compound 2. The synthesized compounds were screened for their antimicrobial activity.

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Year:  2010        PMID: 21169139     DOI: 10.2478/v10007-010-0033-8

Source DB:  PubMed          Journal:  Acta Pharm        ISSN: 1330-0075            Impact factor:   2.230


  2 in total

1.  Antibacterial activity of mother tinctures of cholistan desert plants in pakistan.

Authors:  M Ahmad; Nazia Ghafoor; M N Aamir
Journal:  Indian J Pharm Sci       Date:  2012-09       Impact factor: 0.975

2.  Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-Oxidase.

Authors:  Sangmi Oh; Yumi Park; Curtis A Engelhart; Joshua B Wallach; Dirk Schnappinger; Kriti Arora; Michelle Manikkam; Brian Gac; Hongwu Wang; Nicholas Murgolo; David B Olsen; Michael Goodwin; Michelle Sutphin; Danielle M Weiner; Laura E Via; Helena I M Boshoff; Clifton E Barry
Journal:  J Med Chem       Date:  2018-11-05       Impact factor: 7.446

  2 in total

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