Literature DB >> 21168976

Evaluating the effects of a single copy of a mutation in the myostatin gene (c.*1232G>A) on carcass traits in crossbred lambs.

A Y Masri1, N R Lambe, J M Macfarlane, S Brotherstone, W Haresign, L Bünger.   

Abstract

This study evaluated the effects of the ovine c.*1232G>A myostatin mutation (MM) on carcass traits in heterozygous crossbred lambs sired by Texel and Poll Dorset rams using ultrasound, CT scanning, carcass classification and VIA. In experiment 1, MM was associated with increased loin depth (+2.8%) and area (+3.2%). MM-carriers had significantly higher CT-estimated lean weight and proportion (2 to 4%) and muscle to bone ratio (by ~3%), in both experiments, and muscle to fat ratio (28%) in experiment 2. Muscle areas in three cross-sectional CT scans, were higher (2 to 5%) in MM-carriers. In experiment 2, fat-related measurements were significantly lower in MM-carrier lambs but this was not seen in experiment 1. A significant increase in muscle density, indicative of lower intramuscular fat, in MM-carriers shows that meat quality characteristics need attention. Carrying MM significantly decreased carcass fat scores. VIA did not detect any significant MM effects.
© 2010 The American Meat Science Association. Published by Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 21168976     DOI: 10.1016/j.meatsci.2010.11.019

Source DB:  PubMed          Journal:  Meat Sci        ISSN: 0309-1740            Impact factor:   5.209


  6 in total

Review 1.  Application of myostatin in sheep breeding programs: A review.

Authors:  Younes Miar; Abdolreza Salehi; Davood Kolbehdari; Seyed Ahmad Aleyasin
Journal:  Mol Biol Res Commun       Date:  2014-03

2.  Optimized Cas9:sgRNA delivery efficiently generates biallelic MSTN knockout sheep without affecting meat quality.

Authors:  Shiwei Zhou; Peter Kalds; Qi Luo; Kexin Sun; Xiaoe Zhao; Yawei Gao; Bei Cai; Shuhong Huang; Qifang Kou; Bjoern Petersen; Yulin Chen; Baohua Ma; Xiaolong Wang
Journal:  BMC Genomics       Date:  2022-05-06       Impact factor: 4.547

3.  The comparative results of myostatin introgression from donor Texel to recipient Ramlıç sheep with the aspects of growth, pre-, and post-slaughter carcass traits in the second backcross generation.

Authors:  Mustafa Tekerli; Metin Erdoğan; Serdar Koçak; Koray Çelikeloğlu; Ebubekir Yazıcı; Özlem Hacan; Zehra Bozkurt; Mustafa Demirtaş; Samet Çinkaya
Journal:  Arch Anim Breed       Date:  2022-06-22

4.  Genes contributing to genetic variation of muscling in sheep.

Authors:  Ross L Tellam; Noelle E Cockett; Tony Vuocolo; Christopher A Bidwell
Journal:  Front Genet       Date:  2012-08-29       Impact factor: 4.599

5.  Effects of Intronic SNPs in the Myostatin Gene on Growth and Carcass Traits in Colored Polish Merino Sheep.

Authors:  Ewa Grochowska; Bronisław Borys; Sławomir Mroczkowski
Journal:  Genes (Basel)       Date:  2019-12-18       Impact factor: 4.096

6.  Myostatin regulates fatty acid desaturation and fat deposition through MEF2C/miR222/SCD5 cascade in pigs.

Authors:  Hongyan Ren; Wei Xiao; Xingliang Qin; Gangzhi Cai; Hao Chen; Zaidong Hua; Cheng Cheng; Xinglei Li; Wenjun Hua; Hongwei Xiao; Liping Zhang; Jiali Dai; Xinmin Zheng; Zhe Zhu; Chong Qian; Jie Yao; Yanzhen Bi
Journal:  Commun Biol       Date:  2020-10-23
  6 in total

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