Literature DB >> 21168594

Comparable outcomes in donation after cardiac death and donation after brainstem death: a matched analysis of renal transplants.

J K Pine1, P J Goldsmith, D M Ridgway, A J Cockbain, S Farid, S Fraser, S G Pollard, M Attia, K V Menon, N Ahmad.   

Abstract

Donation after cardiac death (DCD) donors provide a valuable source of grafts for renal transplantation. They are exposed to an initial warm ischemic insult, which can affect early function. We sought to compare our initial DCD experience in renal transplantation with a case-matched donation after brain death (DBD) cohort from the same period. We included all DCD transplantations in the first 5 years of the program. A control DBD group was matched with a variety of donor and recipient factors. We demonstrated a significantly increased early dysfunction (DGF and primary nonfunction). DCD graft function was poorer than the DBD equivalent at 1- and 3-years. However, medium-term recipient and graft outcomes were comparable. DCD grafts continue to play a vital role in renal transplantation despite evidence of early graft dysfunction.
Copyright © 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 21168594     DOI: 10.1016/j.transproceed.2010.09.072

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  2 in total

Review 1.  Kidney donation after cardiac death.

Authors:  Jacob A Akoh
Journal:  World J Nephrol       Date:  2012-06-06

2.  Posttransplant Outcomes of Kidneys Donated After Brain Death Followed by Circulatory Death: A Cohort Study of 128 Chinese Patients.

Authors:  Ning Na; Ke Li; Zhengyu Huang; Bin Miao; Cheng Hu; Heng Li; Dejuan Wang; Jianguang Qiu
Journal:  Transplant Direct       Date:  2017-07-05
  2 in total

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