Literature DB >> 21165632

Treatment of lower extremity long bone nonunion with expandable intramedullary nailing and autologous bone grafting.

Yunfei Niu1, Yushu Bai, Shuogui Xu, Xinwei Liu, Panfeng Wang, Dajiang Wu, Chuncai Zhang, Ming Li.   

Abstract

BACKGROUND: Nonunion of long bones in lower limbs is a common complication of orthopedic trauma that can be extremely debilitating. This retrospective study describes our experience using expandable intramedullary nails and autologous bone grafting in treating lower limb long bone nonunion with bone defects.
METHODS: Nineteen patients (mean age 38.9 years, range 18-61) with lower limb long bone nonunion and defects caused by femoral or tibial fracture types were as follows: A2 (3 femoral, 1 tibial), A3 (1 femoral, 2 tibial), B2 (3 femoral, 4 tibial), and B3 (1 femoral, 4 tibial). Expandable intramedullary nailing and autologous bone (iliac and/or fibular) grafting were used for the treatment. Postoperative bone healing as determined by analysis of standard anteroposterior and lateral X-ray films every 4 weeks. Complications were noted.
RESULTS: The average number of previous surgeries was 1.9 (range 1-4). The mean duration from original injury to treatment was 17.6 months (range 9-40 months). Femoral shaft nonunion healed on average of 26.5 weeks (range 16-60 weeks) after surgery, while tibial shaft nonunion healed on average of 23.6 weeks (range 12-40 weeks) after surgery. Class I healing occurred in all but two patients who experienced chronic postoperative osteomyelitis and delayed wound healing, respectively. Two patients complained of postoperative donor site pain.
CONCLUSIONS: The use of expandable intramedullary nails and autologous bone grafts was an effective method for repair of nonunion of lower limb fractures combining with bone defects with minimal complications.

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Year:  2010        PMID: 21165632     DOI: 10.1007/s00402-010-1226-9

Source DB:  PubMed          Journal:  Arch Orthop Trauma Surg        ISSN: 0936-8051            Impact factor:   3.067


  6 in total

1.  Reamed intramedullary exchange nailing in the operative treatment of aseptic tibial shaft nonunion.

Authors:  Christian Hierholzer; Jan Friederichs; Claudio Glowalla; Alexander Woltmann; Volker Bühren; Christian von Rüden
Journal:  Int Orthop       Date:  2016-10-28       Impact factor: 3.075

2.  A Review of Proximal Tibia Entry Points for Intramedullary Nailing and Validation of The Lateral Parapatellar Approach as Extra-articular.

Authors:  Akshar H Patel; J Heath Wilder; Olivia C Lee; Austin J Ross; Krishna C Vemulapalli; Paul B Gladden; Murphy P Martin; William F Sherman
Journal:  Orthop Rev (Pavia)       Date:  2022-01-30

3.  Human autologous mesenchymal stem cells with extracorporeal shock wave therapy for nonunion of long bones.

Authors:  Lei Zhai; Xin-Long Ma; Chuan Jiang; Bo Zhang; Shui-Tao Liu; Geng-Yan Xing
Journal:  Indian J Orthop       Date:  2016-09       Impact factor: 1.251

Review 4.  Autologous bone graft in the treatment of post-traumatic bone defects: a systematic review and meta-analysis.

Authors:  Matheus Lemos Azi; Alessandro Aprato; Irene Santi; Mauricio Kfuri; Alessandro Masse; Alexander Joeris
Journal:  BMC Musculoskelet Disord       Date:  2016-11-09       Impact factor: 2.362

5.  Multidirectional percutaneous drilling and autologous bone marrow injection for the treatment of femoral diaphyseal nonunions: a prospective interventional study.

Authors:  Ming Li; Yutong Meng; Yi Li; Anhua Long; Houchen Lv; Pengbin Yin; Licheng Zhang; Peifu Tang
Journal:  Ther Clin Risk Manag       Date:  2019-08-19       Impact factor: 2.423

6.  The diaphyseal aseptic tibial nonunions after failed previous treatment options managed with the reamed intramedullary locking nail.

Authors:  Igor Kostic; Milan Mitkovic; Milorad Mitkovic
Journal:  J Clin Orthop Trauma       Date:  2017-08-24
  6 in total

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