Literature DB >> 21164512

Systems biology: Metabolites do social networking.

Douglas B Kell.   

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Year:  2011        PMID： 21164512     DOI： 10.1038/nchembio.505

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  11 in total

1.  Extensive in vivo metabolite-protein interactions revealed by large-scale systematic analyses.

Authors:  Xiyan Li; Tara A Gianoulis; Kevin Y Yip; Mark Gerstein; Michael Snyder
Journal:  Cell       Date:  2010-10-28       Impact factor: 41.582

2.  A chemoinformatics analysis of hit lists obtained from high-throughput affinity-selection screening.

Authors:  Nathan Brown; Hartmut Zehender; Kamal Azzaoui; Ansgar Schuffenhauer; Lorenz M Mayr; Edgar Jacoby
Journal:  J Biomol Screen       Date:  2005-12-16

3.  Metabolomics approach for enzyme discovery.

Authors:  Natsumi Saito; Martin Robert; Sayaka Kitamura; Richard Baran; Tomoyoshi Soga; Hirotada Mori; Takaaki Nishioka; Masaru Tomita
Journal:  J Proteome Res       Date:  2006-08       Impact factor: 4.466

Review 4.  The influence of drug-like concepts on decision-making in medicinal chemistry.

Authors:  Paul D Leeson; Brian Springthorpe
Journal:  Nat Rev Drug Discov       Date:  2007-11       Impact factor: 84.694

Review 5.  'Metabolite-likeness' as a criterion in the design and selection of pharmaceutical drug libraries.

Authors:  Paul D Dobson; Yogendra Patel; Douglas B Kell
Journal:  Drug Discov Today       Date:  2008-12-26       Impact factor: 7.851

Review 6.  Network pharmacology: the next paradigm in drug discovery.

Authors:  Andrew L Hopkins
Journal:  Nat Chem Biol       Date:  2008-11       Impact factor: 15.040

7.  Drug off-target effects predicted using structural analysis in the context of a metabolic network model.

Authors:  Roger L Chang; Li Xie; Lei Xie; Philip E Bourne; Bernhard Ø Palsson
Journal:  PLoS Comput Biol       Date:  2010-09-23       Impact factor: 4.475

8.  Here is the evidence, now what is the hypothesis? The complementary roles of inductive and hypothesis-driven science in the post-genomic era.

Authors:  Douglas B Kell; Stephen G Oliver
Journal:  Bioessays       Date:  2004-01       Impact factor: 4.345

9.  Theodor Bücher Lecture. Metabolomics, modelling and machine learning in systems biology - towards an understanding of the languages of cells. Delivered on 3 July 2005 at the 30th FEBS Congress and the 9th IUBMB conference in Budapest.

Authors:  Douglas B Kell
Journal:  FEBS J       Date:  2006-03       Impact factor: 5.542

10.  Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.

Authors:  Douglas B Kell
Journal:  BMC Med Genomics       Date:  2009-01-08       Impact factor: 3.063
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  2 in total

1.  An analysis of a 'community-driven' reconstruction of the human metabolic network.

Authors:  Neil Swainston; Pedro Mendes; Douglas B Kell
Journal:  Metabolomics       Date:  2013-07-12       Impact factor: 4.290

Review 2.  Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery.

Authors:  Douglas B Kell; Royston Goodacre
Journal:  Drug Discov Today       Date:  2013-07-26       Impact factor: 7.851
  2 in total

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