Literature DB >> 2116162

Use of sodium aurothiomalate during lactation.

P N Bennett1, S J Humphries, J P Osborne, A K Clarke, A Taylor.   

Abstract

The report concerns a mother who breast fed her infant whilst receiving sodium aurothiomalate for the treatment of rheumatoid arthritis. The milk:serum concentration ratio was not constant, reflecting the non-concurrence of the concentration-time profiles of gold in milk and maternal serum after i.m. injection. Gold was detected in the infant's serum. Calculations indicate that the weight-adjusted dose to the infant exceeded that received by the mother.

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Year:  1990        PMID： 2116162      PMCID： PMC1380184          DOI： 10.1111/j.1365-2125.1990.tb03703.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  5 in total

1.  Infants of mothers receiving gold therapy.

Authors:  D L Cohen; J Orzel; A Taylor
Journal:  Arthritis Rheum       Date:  1981-01

2.  Gold secretion in maternal milk.

Authors:  R A Bell; I M Dale
Journal:  Arthritis Rheum       Date:  1976 Nov-Dec

3.  Excretion of gold into human breast milk.

Authors:  M Ostensen; K Skavdal; G Myklebust; Y Tomassen; J Aarbakke
Journal:  Eur J Clin Pharmacol       Date:  1986       Impact factor: 2.953

Review 4.  Drugs in human milk. Clinical pharmacokinetic considerations.

Authors:  H C Atkinson; E J Begg; B A Darlow
Journal:  Clin Pharmacokinet       Date:  1988-04       Impact factor: 6.447

5.  Gold pharmacokinetics in breast milk and serum of a lactating woman.

Authors:  T W Rooney; A Lorber; P Veng-Pedersen; R A Herman; R Meehan; J Hade; A Hade; D E Furst
Journal:  J Rheumatol       Date:  1987-12       Impact factor: 4.666
  5 in total
  1 in total

Review 1.  Optimisation of antirheumatic drug treatment in pregnancy.

Authors:  M Ostesen
Journal:  Clin Pharmacokinet       Date:  1994-12       Impact factor: 6.447
  1 in total

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