Literature DB >> 21161499

At the crossroads of cancer and inflammation: Ras rewires an HIF-driven IL-1 autocrine loop.

Stefan Kaluz1, Erwin G Van Meir.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21161499      PMCID： PMC5424890          DOI： 10.1007/s00109-010-0706-2

Source DB:  PubMed          Journal:  J Mol Med (Berl)        ISSN： 0946-2716            Impact factor:   4.599


× No keyword cloud information.
  12 in total

1.  Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity.

Authors:  Eoin P Cummins; Edurne Berra; Katrina M Comerford; Amandine Ginouves; Kathleen T Fitzgerald; Fergal Seeballuck; Catherine Godson; Jens E Nielsen; Paul Moynagh; Jacques Pouyssegur; Cormac T Taylor
Journal:  Proc Natl Acad Sci U S A       Date:  2006-11-17       Impact factor: 11.205

Review 2.  Genetic and biologic progression in astrocytomas and their relation to angiogenic dysregulation.

Authors:  Daniel J Brat; Amilcar Castellano-Sanchez; Balveen Kaur; Erwin G Van Meir
Journal:  Adv Anat Pathol       Date:  2002-01       Impact factor: 3.875

3.  HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.

Authors:  M Ivan; K Kondo; H Yang; W Kim; J Valiando; M Ohh; A Salic; J M Asara; W S Lane; W G Kaelin
Journal:  Science       Date:  2001-04-05       Impact factor: 47.728

4.  Ras regulates interleukin-1β-induced HIF-1α transcriptional activity in glioblastoma.

Authors:  Vivek Sharma; Deobrat Dixit; Nitin Koul; Veer Singh Mehta; Ellora Sen
Journal:  J Mol Med (Berl)       Date:  2010-09-24       Impact factor: 4.599

Review 5.  Hypoxia inducible factor-1: a novel target for cancer therapy.

Authors:  Vladimir E Belozerov; Erwin G Van Meir
Journal:  Anticancer Drugs       Date:  2005-10       Impact factor: 2.248

Review 6.  Cytokines and tumors of the central nervous system.

Authors:  E G Van Meir
Journal:  Glia       Date:  1995-11       Impact factor: 7.452

7.  NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha.

Authors:  Jordi Rius; Monica Guma; Christian Schachtrup; Katerina Akassoglou; Annelies S Zinkernagel; Victor Nizet; Randall S Johnson; Gabriel G Haddad; Michael Karin
Journal:  Nature       Date:  2008-04-23       Impact factor: 49.962

8.  IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis.

Authors:  Yun-Jin Jung; Jennifer S Isaacs; Sunmin Lee; Jane Trepel; Len Neckers
Journal:  FASEB J       Date:  2003-09-04       Impact factor: 5.191

Review 9.  Targeting HIF-1 for cancer therapy.

Authors:  Gregg L Semenza
Journal:  Nat Rev Cancer       Date:  2003-10       Impact factor: 60.716

10.  Expression and release of interleukin-1 by human glioblastoma cells in vitro and in vivo.

Authors:  T Gauthier; M F Hamou; L Monod; P Gallay; S Carrel; N de Tribolet
Journal:  Acta Neurochir (Wien)       Date:  1993       Impact factor: 2.216
View more
  6 in total

1.  Farnesyltransferase inhibitor manumycin targets IL1β-Ras-HIF-1α axis in tumor cells of diverse origin.

Authors:  Vivek Sharma; Sk Sudipta Shaheen; Deobrat Dixit; Ellora Sen
Journal:  Inflammation       Date:  2012-04       Impact factor: 4.092

2.  Mild systemic inflammation and moderate hypoxia transiently alter neuronal excitability in mouse somatosensory cortex.

Authors:  Jérôme Mordel; Aminah Sheikh; Simeon Tsohataridis; Patrick O Kanold; Christoph M Zehendner; Heiko J Luhmann
Journal:  Neurobiol Dis       Date:  2016-01-04       Impact factor: 5.996

3.  Functional characterization of human Cd33+ and Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines.

Authors:  Melissa G Lechner; Carolina Megiel; Sarah M Russell; Brigid Bingham; Nicholas Arger; Tammy Woo; Alan L Epstein
Journal:  J Transl Med       Date:  2011-06-09       Impact factor: 5.531

4.  Anti-Inflammatory Effects of Huangqin Decoction on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice Through Regulation of the Gut Microbiota and Suppression of the Ras-PI3K-Akt-HIF-1α and NF-κB Pathways.

Authors:  Min-Yao Li; Hui-Juan Luo; Xue Wu; Yu-Hong Liu; Yu-Xuan Gan; Nan Xu; Yao-Min Zhang; Shu-Hua Zhang; Chang-Lin Zhou; Zi-Ren Su; Xiao-Qi Huang; Xue-Bao Zheng
Journal:  Front Pharmacol       Date:  2020-01-20       Impact factor: 5.810

Review 5.  A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.

Authors:  Richard E Kast; John A Boockvar; Ansgar Brüning; Francesco Cappello; Wen-Wei Chang; Boris Cvek; Q Ping Dou; Alfonso Duenas-Gonzalez; Thomas Efferth; Daniele Focosi; Seyed H Ghaffari; Georg Karpel-Massler; Kirsi Ketola; Alireza Khoshnevisan; Daniel Keizman; Nicolas Magné; Christine Marosi; Kerrie McDonald; Miguel Muñoz; Ameya Paranjpe; Mohammad H Pourgholami; Iacopo Sardi; Avishay Sella; Kalkunte S Srivenugopal; Marco Tuccori; Weiguang Wang; Christian R Wirtz; Marc-Eric Halatsch
Journal:  Oncotarget       Date:  2013-04

6.  A New Role for Helicobacter pylori Urease: Contributions to Angiogenesis.

Authors:  Deiber Olivera-Severo; Augusto F Uberti; Miguel S Marques; Marta T Pinto; Maria Gomez-Lazaro; Céu Figueiredo; Marina Leite; Célia R Carlini
Journal:  Front Microbiol       Date:  2017-09-27       Impact factor: 5.640
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.