AIM: To translate into Greek and validate the chronic liver disease questionnaire (CLDQ). METHODS: Two hundred and six consecutive adult patients with the diagnosis of a chronic liver disease from 2 general hospitals in Athens were enrolled in the study from May to September 2008. In order to assess their quality of life (QOL) the CLDQ was applied. The instrument was translated from English, back translated and reviewed in focus groups within the framework of a large multicenter study. The measurements that were performed included: 2 independent sample t tests, one-way analysis of variance, reliability coefficients, explanatory factor analysis using a varimax rotation and the principal components method. RESULTS: One hundred and twenty five (61%) patients were men, half were aged 40-59 years and > 33% were > 60 years old. Among the patients, 48 (23%) were hospitalized and 97 (47%) were cirrhotic according to the Child-Pugh score. The internal consistency of the Greek CLDQ version using Cronbach's alpha coefficient was found to be 0.93. Exploratory factor analysis identified 7 domains accounting for 65% of the variance of CLDQ items and only partially overlapping with those found in the original version. The area under the receiver operating characteristics curve was calculated at 0.813 and the logistic estimate for the threshold score of 167.50 provided a sensitivity of 74.3% and a specificity of 71.6% for the model. CONCLUSION: Our data confirmed the validity of the Greek version of the CLDQ in identifying the QOL among patients with chronic liver disease.
AIM: To translate into Greek and validate the chronic liver disease questionnaire (CLDQ). METHODS: Two hundred and six consecutive adult patients with the diagnosis of a chronic liver disease from 2 general hospitals in Athens were enrolled in the study from May to September 2008. In order to assess their quality of life (QOL) the CLDQ was applied. The instrument was translated from English, back translated and reviewed in focus groups within the framework of a large multicenter study. The measurements that were performed included: 2 independent sample t tests, one-way analysis of variance, reliability coefficients, explanatory factor analysis using a varimax rotation and the principal components method. RESULTS: One hundred and twenty five (61%) patients were men, half were aged 40-59 years and > 33% were > 60 years old. Among the patients, 48 (23%) were hospitalized and 97 (47%) were cirrhotic according to the Child-Pugh score. The internal consistency of the Greek CLDQ version using Cronbach's alpha coefficient was found to be 0.93. Exploratory factor analysis identified 7 domains accounting for 65% of the variance of CLDQ items and only partially overlapping with those found in the original version. The area under the receiver operating characteristics curve was calculated at 0.813 and the logistic estimate for the threshold score of 167.50 provided a sensitivity of 74.3% and a specificity of 71.6% for the model. CONCLUSION: Our data confirmed the validity of the Greek version of the CLDQ in identifying the QOL among patients with chronic liver disease.
Authors: P Rucci; G Taliani; L Cirrincione; A Alberti; D Bartolozzi; N Caporaso; M Colombo; R Coppola; M Chiaramonte; A Craxi; I De Sio; A R Floreani; G B Gaeta; M Persico; G Secchi; I Versace; A Mele Journal: Dig Liver Dis Date: 2005-10-10 Impact factor: 4.088
Authors: Samantha Mucci; Vanessa de Albuquerque Citero; Adriano Miziara Gonzalez; Luciana Geocze; Stephan Geocze; Gaspar de Jesus Lopes Filho; Mario Alfredo De Marco; Edison Roberto Parise; Luiz Antonio Nogueira Martins Journal: Qual Life Res Date: 2012-03-03 Impact factor: 4.147
Authors: Hilda Mahmoudi; Peyman Jafari; Mahvash Alizadeh-Naini; Siyavash Gholami; Seyed Ali Malek-Hosseini; Sina Ghaffaripour Journal: Qual Life Res Date: 2011-11-13 Impact factor: 4.147
Authors: Dusan Dj Popovic; Nada V Kovacevic; Darija B Kisic Tepavcevic; Goran Z Trajkovic; Tamara M Alempijevic; Milan M Spuran; Miodrag N Krstic; Rada S Jesic; Zobair M Younossi; Tatjana D Pekmezovic Journal: World J Gastroenterol Date: 2013-08-14 Impact factor: 5.742