Literature DB >> 21154160

Small non-coding RNAs in disease development and host-pathogen interactions.

Mathieu Rederstorff1, Alexander Hüttenhofer.   

Abstract

Non-coding RNAs (ncRNAs) play critical roles in all physiological processes. Many ncRNAs have also been implicated in a variety of pathological disorders, including cancer. This review provides an overview of the roles of small ncRNAs in infectious diseases and genetic disorders, including diseases of the CNS and various cancers. There is a focus on the consequences of microRNA (miRNA) de-regulation in human diseases, and recent progress in understanding other disease-related classes of ncRNAs, such as small nucleolar RNAs (snoRNAs), is presented. Finally, this review provides a brief perspective on new and powerful diagnostic strategies for human diseases that are based on ncRNA analysis, and presents novel potential approaches using ncRNAs as tools or targets for the treatment of such diseases.

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Year:  2010        PMID： 21154160

Source DB:  PubMed          Journal:  Curr Opin Mol Ther        ISSN： 1464-8431


  11 in total

1.  Computer-assisted annotation of murine Sertoli cell small RNA transcriptome.

Authors:  Nicole Ortogero; Grant W Hennig; Chad Langille; Seungil Ro; John R McCarrey; Wei Yan
Journal:  Biol Reprod       Date:  2013-01-03       Impact factor: 4.285

Review 2.  Analysis of the transcriptome in molecular epidemiology studies.

Authors:  Cliona M McHale; Luoping Zhang; Reuben Thomas; Martyn T Smith
Journal:  Environ Mol Mutagen       Date:  2013-08-01       Impact factor: 3.216

3.  Coding and noncoding expression patterns associated with rare obesity-related disorders: Prader-Willi and Alström syndromes.

Authors:  Merlin G Butler; Kun Wang; Jan D Marshall; Jürgen K Naggert; Jasmine A Rethmeyer; Sumedha S Gunewardena; Ann M Manzardo
Journal:  Adv Genomics Genet       Date:  2015

Review 4.  Role of transcribed ultraconserved regions in gastric cancer and therapeutic perspectives.

Authors:  Shen-Shuo Gao; Zhi-Kai Zhang; Xu-Bin Wang; Yan Ma; Guo-Qing Yin; Xiao-Bo Guo
Journal:  World J Gastroenterol       Date:  2022-07-07       Impact factor: 5.374

5.  A Platform for Discovery and Quantification of Modified Ribonucleosides in RNA: Application to Stress-Induced Reprogramming of tRNA Modifications.

Authors:  Weiling Maggie Cai; Yok Hian Chionh; Fabian Hia; Chen Gu; Stefanie Kellner; Megan E McBee; Chee Sheng Ng; Yan Ling Joy Pang; Erin G Prestwich; Kok Seong Lim; I Ramesh Babu; Thomas J Begley; Peter C Dedon
Journal:  Methods Enzymol       Date:  2015-07-17       Impact factor: 1.600

6.  Expression Profiling of a Heterogeneous Population of ncRNAs Employing a Mixed DNA/LNA Microarray.

Authors:  Konstantinia Skreka; Marek Zywicki; Michael Karbiener; Alexander Hüttenhofer; Marcel Scheideler; Mathieu Rederstorff
Journal:  J Nucleic Acids       Date:  2012-06-10

7.  The Unexpected Tuners: Are LncRNAs Regulating Host Translation during Infections?

Authors:  Primoz Knap; Toma Tebaldi; Francesca Di Leva; Marta Biagioli; Mauro Dalla Serra; Gabriella Viero
Journal:  Toxins (Basel)       Date:  2017-11-03       Impact factor: 4.546

8.  Systematic transcriptome wide analysis of lncRNA-miRNA interactions.

Authors:  Saakshi Jalali; Deeksha Bhartiya; Mukesh Kumar Lalwani; Sridhar Sivasubbu; Vinod Scaria
Journal:  PLoS One       Date:  2013-02-06       Impact factor: 3.240

9.  Long Non-Coding RNAs in Infection Biology.

Authors:  Vinod Scaria; Ayesha Pasha
Journal:  Front Genet       Date:  2013-01-09       Impact factor: 4.599

10.  The role of viral and host microRNAs in the Aujeszky's disease virus during the infection process.

Authors:  Oriol Timoneda; Fernando Núñez-Hernández; Ingrid Balcells; Marta Muñoz; Anna Castelló; Gonzalo Vera; Lester J Pérez; Raquel Egea; Gisela Mir; Sarai Córdoba; Rosa Rosell; Joaquim Segalés; Anna Tomàs; Armand Sánchez; José I Núñez
Journal:  PLoS One       Date:  2014-01-24       Impact factor: 3.240
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